Program at a glance
The ISOO 2022 Congress will take place from Friday, June 17 - Tuesday, June 21, 2022 in Leiden, The Netherlands. Please click on the image below for the full program at a glance. An overview of the sessions can be found below.
Saturday, June 18, 2022
08:00 a.m. - 08:45 a.m.
Johannes Vermeer and Frans van Mieris
Newcomer Session: Introduction to the ISOO and History of Ocular Oncology
08:00 a.m. - 08:02 a.m.
Welcome
Presenter:
Dan S. Gombos (United States)
08:02 a.m. - 08:15 a.m.
History of ISOO
Presenter:
Koby Pe'er (Israel)
08:15 a.m. - 08:30 a.m.
Historic evelopments in Uveal Melanoma
Presenter:
Bertil Damato (United Kingdom/Sweden)
08:30 a.m. - 08:45 a.m.
Historic developments in Retinoblastoma
Presenter:
Francis Munier (Switzerland)
08:00 a.m. - 08:50 a.m.
Willem van de Velde
Coffee with Experts - Imaging of Rb, Uveal Melanoma, Eyelids
08:00 a.m. - 08:15 a.m.
Imaging in retinoblastoma
Presenter:
Pim de Graaf (The Netherlands)
08:15 a.m. - 08:30 a.m.
Imaging in uveal melanoma
Presenter:
Jan-Willem Beenakker (The Netherlands)
08:30 a.m. - 08:40 a.m.
MR and CT imaging of the normal eyelid and its application in eyelid tumors
Presenter:
Teresa Gonçalves Ferreira (The Netherlands)
08:40 a.m. - 08:50 a.m.
Ultrasound guidance of plaque placement for choroidal melanoma
Presenter:
Brian Marr (United States)
08:00 a.m. - 09:00 a.m.
Jan Steen
Poster session Retinoblastoma 1.1
Moderators:
Eva Biewald (Germany), Emine Kiliç (The Netherlands) & Ankit Singh Tomar (India)
Global retinoblastoma treatment outcomes: Association with national income level
Presenter:
Ankit Singh Tomar (India)
Clinical features in advanced retinoblastoma: High risk pathology and metastatic death
Presenter:
Ankit Singh Tomar (India)
Combined intravitreal chemotherapy with carboplatin plus melphalan for management of vitreous seeding in retinoblastoma
Presenter:
Babak Masoomian (Iran)
Intravitreal carboplatin as salvage treatment for progressive vitreous disease in retinoblastoma: A phase I clinical trial
Presenter:
Benjamin King (United States)
Intravitreal chemotherapy eligibility and ocular survival for advanced retinoblastoma
Presenter:
Benjamin King (United States)
Correlation of neuroimaging and histopathologic risk factors of advanced group E retinoblastoma
Presenter:
Eva Biewald (Germany)
Bilateral retinoblastoma: The challenge of managment in sub-Saharan Africa support unit
Presenter:
Fatoumata Sylla (Mali)
08:00 a.m. - 09:00 a.m.
Godfried Schalcken
Poster session Retinoblastoma 1.2
Moderators:
Nathalie Cassoux (France), M. Ashwin Reddy (United Kingdom) & Luiz Teixeira (Brazil)
Outcomes of tandem intravitreal chemotherapy for refractory vitreous seeds in retinoblastoma
Presenter:
Gaurav Garg (India)
Association of RB1 rs9568036 and CDKN1A rs1801270 polymorphisms to retinoblastoma susceptibility
Presenter:
Golnaz Khakpour (Iran)
Ruthenium plaque brachytherapy in the current era of retinoblastoma treatment
Presenter:
Guy Negretti (United Kingdom)
Understanding the age of the tumour occurrences in familial retinoblastoma in a single-centre retinoblastoma service
Presenter:
Jessica Walker (United Kingdom)
Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
Presenter:
Jiayan Fan (China)
Clinical presentation and outcome of retinoblastoma in older children
Presenter:
Luiz Teixeira (Brazil)
The impact of children with pseudoretinoblastoma presenting to a retinoblastoma unit
Presenter:
M. Ashwin Reddy (United Kingdom)
Central nervous system invasion in retinoblastoma – A case report
Presenter:
Maria Teresa Bonanomi (Brazil)
08:00 a.m. - 09:00 a.m.
Pieter van Slingelandt
Poster session Retinoblastoma 1.3
Moderators:
Machteld Bosscha (The Netherlands), Carol L. Shields (United States) & Matthew Wilson (United States)
Extending the reach: The impact of orbis Cybersight over on global retinoblastoma over two decades
Presenter:
Matthew Wilson (United States)
Familial retinoblastoma: Variations in clinical presentation and management based on maternal versus paternal inheritance
Presenter:
Carol L. Shields (United States)
Correlation of clinical and histopathological risk factors and the role of adjuvant therapy in the era of secondary enucleation for retinoblastoma
Presenter:
Rolika Bansal (India)
Differences in childhood growth parameters between patients with sporadic and heritable retinoblastoma
Presenter:
Roxana Hicks (United States)
Radiotherapy after high dose chemotherapy and stem cell rescue (HDC-ASCT) may improve survival in patients with CNS retinoblastoma – A single center experience
Presenter:
Ira Dunkel (United States)
Formation of a global retinoblastoma advisory group
Presenter:
Matthew Wilson (United States)
Eye preservation therapy for unilateral retinoblastoma
Presenter:
Shigenobu Suzuki (Japan)
Chromosome 6p amplification detected in blood cell-free DNA in advanced retinoblastoma
Presenter:
Shreya Sirivolu (United States)
Histopathologic observations of intra arterial chemotherapy in a xenograft rabbit retinoblastoma model
Presenter:
Stephen Chen (United States)
09:00 a.m. - 10:30 a.m.
Johannes Vermeer and Frans van Mieris
S6 Retinoblastoma
Moderators:
Jasmine Francis (United States), Dan S. Gombos (United States), Annette Moll (The Netherlands) & Carol L. Shields (United States)
09:00 a.m. - 09:08 a.m.
Tenfold increased risk for subsequent primary malignancies in survivors of heritable retinoblastoma; an update of the Dutch nationwide cohort
Presenter:
Milo van Hoefen Wijsard (The Netherlands)
09:08 a.m. - 09:16 a.m.
Lack of complete response pre-transplant is not associated with inferior overall survival for stage 4a metastatic retinoblastoma
Presenter:
Ira Dunkel (United States)
09:16 a.m. - 09:24 a.m.
Tylectomy for salvage of eyes with retinoblastoma
Presenter:
Zhao Xun Feng (Canada)
09:24 a.m. - 09:32 a.m.
Comparison of intravenous and intraarterial chemotherapy: Results from 1080 patients from 54 countries
Presenter:
Andrew Stacey (United States)
09:32 a.m. - 09:40 a.m.
Aqueous seeding in retinoblastoma: Classification and clinicopathological correlation
Presenter:
Swathi Kaliki (India)
09:40 a.m. - 09:48 a.m.
Impact of chemotherapy on secondary primary malignancies in patients with germline retinoblastoma
Presenter:
Dan S. Gombos (United States)
09:48 a.m. - 09:56 a.m.
Eye globe salvage in advanced group E retinoblastoma
Presenter:
Theodora Hadjistilianou (Italy)
09:56 a.m. - 10:04 a.m.
Single-center, long-term, real-world outcomes of intravenous and/or intra-arterial chemotherapy for retinoblastoma - Does it last to 10 or 20 years?
Presenter:
Carol L. Shields (United States)
10:04 a.m. - 10:12 a.m.
At what age could screening of children at risk for familial retinoblastoma be stopped?
Presenter:
Annette Moll (The Netherlands)
10:12 a.m. - 10:20 a.m.
In vivo imaging of anterior segment invasion in retinoblastoma: Description of the invasion profiles and implications for therapeutic decision-making
Presenter:
Francis Munier (Switzerland)
10:20 a.m. - 10:28 a.m.
Primary orbital retinoblastoma - Long-term outcome of Intensive Multimodal Treatment Protocol (IMTP)
Presenter:
Fairooz P Manjandavida (India)
09:00 a.m. - 10:30 a.m.
Jan Steen
Poster session Uveal Melanoma 1.1
Moderators:
Nikos Bechrakis (Germany), Amy Schefler (United States) & Basil Williams (United States)
Tissue glue adhesion for plaque brachytherapy of uveal melanoma in humans, an initial experience
Presenter:
Kushal Agrawal (United States)
Preferentially Expressed Antigen in Melanoma (PRAME) immunohistochemistry labeling in uveal melanomas
Presenter:
Saman Ahmadian (United States)
106-Ruthenium brachytherapy in large uveal melanoma
Presenter:
Nikos Bechrakis (Germany)
Potential of aqueous humor as a liquid biopsy for uveal melanoma
Presenter:
Jesse Berry (United States)
Staged brachytherapy: A novel approach for large uveal melanoma
Presenter:
Maria Bretana (United States)
Combined GEP and PRAME testing creates high-risk stratification for half of uveal melanoma patients
Presenter:
Peter Hovland (United States)
Randomized trial of treat-and extend intravitreal aflibercept for radiation retinopathy: One year outcomes
Presenter:
Amy Schefler (United States)
Macrophage migration-inhibitory factor (MIF): Expression in high risk UM
Presenter:
Zahra Souri (Iran)
Evaluation of outcomes following implementation of a nurse-led oncology clinic during COVID-19
Presenter:
Osman Younus (United Kingdom)
Survey of fine needle aspiration biopsy techniques for intraocular tumors
Presenter:
Basil Williams (United States)
Cytogenetic evidence of the higher metastatic risk in the ciliary body involved uveal melanoma
Presenter:
An-Ning Chao (Taiwan)
09:00 a.m. - 10:30 a.m.
Godfried Schalcken
Poster session Uveal Melanoma 1.2
Moderators:
Marem Chionkhumi Christy (India), Martyna Elas (Poland) & Gre Luyten (The Netherlands)
Melanocytoma co-existing in choroidal melanoma
Presenter:
Marem Chionkhumi Christy (India)
Uveal melanoma prognostication: GEP vs NGS
Presenter:
Jacquelyn Davanzo (United States)
Outpatient ocular brachytherapy
Presenter:
Richard Jennelle (United States)
Conformal plaque brachytherapy outcomes for peripapillary choroidal melanoma
Presenter:
Emily Liao (Canada)
Long term follow-up of circumscribed iris melanomas treated by proton beam therapy
Presenter:
Livia Lumbroso-le Rouic (France)
The impact of the COVID-19 pandemic on diagnosis and treatment of choroidal melanoma patients in the Netherlands
Presenter:
Gre Luyten (The Netherlands)
Uveal melanoma metastasis to the contralateral eye structures: A retrospective comparative analysis of 13 consecutive patients
Presenter:
Babak Masoomian (Iran)
Post-enucleation radiotherapy for uveal melanoma with extrascleral extension
Presenter:
Deep Sarode (United Kingdom)
Next generation preclinical models of uveal melanoma
Presenter:
Małgorzata Szczygieł (Poland)
Long-term results in the treatment of radiation-induced maculopathy with Fluocinolone Acetonide
Presenter:
Lena Zimmermann (Germany)
Patient satisfaction with teleophthalmology in ocular oncology
Presenter:
Paige Campbell (Canada)
09:00 a.m. - 10:30 a.m.
Pieter van Slingelandt
Poster session Uveal Melanoma 1.3
Moderators:
Niels Brouwer (The Netherlands), Jared Ebert (United States) & Raffaele Parrozzani (Italy)
Gene expression profile class changes on interval biopsies of choroidal melanomas
Presenter:
Jared Ebert (United States)
Proton beam radiotherapy treatment of iris melanoma
Presenter:
Katharina Eibenberger (United Kingdom)
Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations in uveal melanoma
Presenter:
Rosaria Gangemi (Italy)
Key clinical concepts from multi-institutional experience with dedicated fixed low-energy proton ocular beamlines
Presenter:
Kavita Mishra (United States)
Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma
Presenter:
Kavita Mishra (United States)
Ruthenium-106 plaque radiotherapy for uveal melanoma: Analysis of tumor thickness and location on anatomical and functional results
Presenter:
Masood Naseripour (Iran)
Hyperreflective Retinal Foci Detected by SD-OCT anticipate radiation-induced macular edema
Presenter:
Raffaele Parrozzani (Italy)
Radiation dose correlation to radiation induced ocular complications
Presenter:
Ekaterina Sokolenko (Germany)
Uveal melanoma: Evidence of cure
Presenter:
Emily Zabor (United States)
Diagnosis of small choroidal melanoma : A machine learning based prediction model
Presenter:
Emily Zabor (United States)
10:30 a.m. - 11:00 a.m.
Coffee break
10:30 a.m. - 11:00 a.m.
Jan Steen
Poster session Retinoblastoma 1.1 - cont.
Moderators:
Eva Biewald (Germany), Emine Kiliç (The Netherlands) & Ankit Singh Tomar (India)
Global retinoblastoma treatment outcomes: Association with national income level
Presenter:
Ankit Singh Tomar (India)
Clinical features in advanced retinoblastoma: High risk pathology and metastatic death
Presenter:
Ankit Singh Tomar (India)
Combined intravitreal chemotherapy with carboplatin plus melphalan for management of vitreous seeding in retinoblastoma
Presenter:
Babak Masoomian (Iran)
Intravitreal carboplatin as salvage treatment for progressive vitreous disease in retinoblastoma: A phase I clinical trial
Presenter:
Benjamin King (United States)
Intravitreal chemotherapy eligibility and ocular survival for advanced retinoblastoma
Presenter:
Benjamin King (United States)
Correlation of neuroimaging and histopathologic risk factors of advanced group E retinoblastoma
Presenter:
Eva Biewald (Germany)
Bilateral retinoblastoma: The challenge of managment in sub-Saharan Africa support unit
Presenter:
Fatoumata Sylla (Mali)
10:30 a.m. - 11:00 a.m.
Godfried Schalcken
Poster session Retinoblastoma 1.2 - cont.
Moderators:
Nathalie Cassoux (France), M. Ashwin Reddy (United Kingdom) & Luiz Teixeira (Brazil)
Outcomes of tandem intravitreal chemotherapy for refractory vitreous seeds in retinoblastoma
Presenter:
Gaurav Garg (India)
Association of RB1 rs9568036 and CDKN1A rs1801270 polymorphisms to retinoblastoma susceptibility
Presenter:
Golnaz Khakpour (Iran)
Ruthenium plaque brachytherapy in the current era of retinoblastoma treatment
Presenter:
Guy Negretti (United Kingdom)
Understanding the age of the tumour occurrences in familial retinoblastoma in a single-centre retinoblastoma service
Presenter:
Jessica Walker (United Kingdom)
Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
Presenter:
Jiayan Fan (China)
Clinical presentation and outcome of retinoblastoma in older children
Presenter:
Luiz Teixeira (Brazil)
The impact of children with pseudoretinoblastoma presenting to a retinoblastoma unit
Presenter:
M. Ashwin Reddy (United Kingdom)
Central nervous system invasion in retinoblastoma – A case report
Presenter:
Maria Teresa Bonanomi (Brazil)
10:30 a.m. - 11:00 a.m.
Pieter van Slingelandt
Poster session Retinoblastoma 1.3 - cont.
Moderators:
Machteld Bosscha (The Netherlands), Carol L. Shields (United States) & Matthew Wilson (United States)
Extending the reach: The impact of orbis Cybersight over on global retinoblastoma over two decades
Presenter:
Matthew Wilson (United States)
Familial retinoblastoma: Variations in clinical presentation and management based on maternal versus paternal inheritance
Presenter:
Carol L. Shields (United States)
Correlation of clinical and histopathological risk factors and the role of adjuvant therapy in the era of secondary enucleation for retinoblastoma
Presenter:
Rolika Bansal (India)
Differences in childhood growth parameters between patients with sporadic and heritable retinoblastoma
Presenter:
Roxana Hicks (United States)
Radiotherapy after high dose chemotherapy and stem cell rescue (HDC-ASCT) may improve survival in patients with CNS retinoblastoma – A single center experience
Presenter:
Ira Dunkel (United States)
Formation of a global retinoblastoma advisory group
Presenter:
Sarah Huemmer (United States)
Eye preservation therapy for unilateral retinoblastoma
Presenter:
Shigenobu Suzuki (Japan)
Chromosome 6p amplification detected in blood cell-free DNA in advanced retinoblastoma
Presenter:
Shreya Sirivolu (United States)
Histopathologic observations of intra arterial chemotherapy in a xenograft rabbit retinoblastoma model
Presenter:
Stephen Chen (United States)
11:00 a.m. - 11:40 a.m.
Johannes Vermeer and Frans van Mieris
S7 Opening Ceremony
11:00 a.m. - 11:03 a.m.
President ISOO Congress
Presenter:
Martine Jager (The Netherlands)
11:03 a.m. - 11:06 a.m.
Chairman Ophthalmology Department Leiden
Presenter:
Gre Luyten (The Netherlands)
11:06 a.m. - 11:09 a.m.
ISOO Congres Program
Presenter:
Vicktoria (vicky) Vishnevskia-Dai (Israel)
11:09 a.m. - 11:12 a.m.
President EURbG
Presenter:
Maya Beck-Popovic (Switzerland)
11:12 a.m. - 11:15 a.m.
President OOG
Presenter:
Steffen Heegaard (Denmark)
11:15 a.m. - 11:25 a.m.
President ARVO
Presenter:
Hans Grossniklaus (United States)
11:25 a.m. - 11:30 a.m.
President ISOO
Presenter:
Dan S. Gombos (United States)
11:30 a.m. - 11:32 a.m.
President ISOO Congress
Presenter:
Martine Jager (The Netherlands)
11:32 a.m. - 11:42 a.m.
Closing the health gap: the role of diversity in Ophthalmology
Presenter:
Basil Williams (United States)
11:42 a.m. - 11:52 a.m.
Women in medicine in Ancient Greece: legendary figures between myths and history
Presenter:
Theodora Hadjistilianou (Italy)
11:52 a.m. - 12:02 p.m.
Women in Ophthalmic Oncology
Presenter:
Carol L. Shields (United States)
12:02 p.m. - 12:12 p.m.
Victoria Lendrum Cohen Award
Presenter:
Nick Rapley (United Kingdom)
11:00 a.m. - 12:30 p.m.
Jan Steen
Poster session Uveal Melanoma 1.1 - cont.
Moderators:
Nikos Bechrakis (Germany), Amy Schefler (United States) & Basil Williams (United States)
Tissue glue adhesion for plaque brachytherapy of uveal melanoma in humans, an initial experience
Presenter:
Kushal Agrawal (United States)
Preferentially Expressed Antigen in Melanoma (PRAME) immunohistochemistry labeling in uveal melanomas
Presenter:
Saman Ahmadian (United States)
106-Ruthenium brachytherapy in large uveal melanoma
Presenter:
Nikos Bechrakis (Germany)
Potential of aqueous humor as a liquid biopsy for uveal melanoma
Presenter:
Jesse Berry (United States)
Staged brachytherapy: A novel approach for large uveal melanoma
Presenter:
Maria Bretana (United States)
Combined GEP and PRAME testing creates high-risk stratification for half of uveal melanoma patients
Presenter:
Peter Hovland (United States)
Randomized trial of treat-and extend intravitreal aflibercept for radiation retinopathy: One year outcomes
Presenter:
Amy Schefler (United States)
Macrophage migration-inhibitory factor (MIF): Expression in high risk UM
Presenter:
Zahra Souri (Iran)
Evaluation of outcomes following implementation of a nurse-led oncology clinic during COVID-19
Presenter:
Osman Younus (United Kingdom)
Survey of fine needle aspiration biopsy techniques for intraocular tumors
Presenter:
Basil Williams (United States)
Cytogenetic evidence of the higher metastatic risk in the ciliary body involved uveal melanoma
Presenter:
An-Ning Chao (Taiwan)
11:00 a.m. - 12:30 p.m.
Godfried Schalcken
Poster session Uveal Melanoma 1.2 - cont.
Moderators:
Marem Chionkhumi Christy (India), Martyna Elas (Poland) & Gre Luyten (The Netherlands)
Melanocytoma co-existing in choroidal melanoma
Presenter:
Marem Chionkhumi Christy (India)
Uveal melanoma prognostication: GEP vs NGS
Presenter:
Jacquelyn Davanzo (United States)
Outpatient ocular brachytherapy
Presenter:
Richard Jennelle (United States)
Conformal plaque brachytherapy outcomes for peripapillary choroidal melanoma
Presenter:
Emily Liao (Canada)
Long term follow-up of circumscribed iris melanomas treated by proton beam therapy
Presenter:
Livia Lumbroso-le Rouic (France)
The impact of the COVID-19 pandemic on diagnosis and treatment of choroidal melanoma patients in the Netherlands
Presenter:
Gre Luyten (The Netherlands)
Uveal melanoma metastasis to the contralateral eye structures: A retrospective comparative analysis of 13 consecutive patients
Presenter:
Babak Masoomian (Iran)
Post-enucleation radiotherapy for uveal melanoma with extrascleral extension
Presenter:
Deep Sarode (United Kingdom)
Next generation preclinical models of uveal melanoma
Presenter:
Małgorzata Szczygieł (Poland)
Long-term results in the treatment of radiation-induced maculopathy with Fluocinolone Acetonide
Presenter:
Lena Zimmermann (Germany)
Patient satisfaction with teleophthalmology in ocular oncology
Presenter:
Paige Campbell (Canada)
11:00 a.m. - 12:30 p.m.
Pieter van Slingelandt
Poster session Uveal Melanoma 1.3 - cont.
Moderators:
Niels Brouwer (The Netherlands), Jared Ebert (United States) & Raffaele Parrozzani (Italy)
Gene expression profile class changes on interval biopsies of choroidal melanomas
Presenter:
Jared Ebert (United States)
Proton beam radiotherapy treatment of iris melanoma
Presenter:
Katharina Eibenberger (United Kingdom)
Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations in uveal melanoma
Presenter:
Rosaria Gangemi (Italy)
Key clinical concepts from multi-institutional experience with dedicated fixed low-energy proton ocular beamlines
Presenter:
Kavita Mishra (United States)
Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma
Presenter:
Kavita Mishra (United States)
Ruthenium-106 plaque radiotherapy for uveal melanoma: Analysis of tumor thickness and location on anatomical and functional results
Presenter:
Masood Naseripour (Iran)
Hyperreflective Retinal Foci Detected by SD-OCT anticipate radiation-induced macular edema
Presenter:
Raffaele Parrozzani (Italy)
Radiation dose correlation to radiation induced ocular complications
Presenter:
Ekaterina Sokolenko (Germany)
Uveal melanoma: Evidence of cure
Presenter:
Emily Zabor (United States)
Diagnosis of small choroidal melanoma : A machine learning based prediction model
Presenter:
Emily Zabor (United States)
12:30 p.m. - 01:40 p.m.
Lunch
12:30 p.m. - 01:40 p.m.
Jan Steen
YOO Lunch
12:30 p.m. - 01:40 p.m.
Panel discussion on post-fellowship and early career challenges
Presenters:
Mary Beth Aronow (United States), Ido Didi Fabian (Israel), Swathi Kaliki (India), Andrew Stacey (United States) & Christina Stathopoulos (Switzerland)
12:30 p.m. - 01:40 p.m.
Godfried Schalcken
Poster session Retinoblastoma 2.1
Moderators:
Helen Dimaras (Canada) & Ido Didi Fabian (Israel)
Identification of novel genes by targeted exome sequencing in retinoblastoma
Presenter:
Bhavna Chawla (India)
Ab interno non filtrating glaucoma surgery for the treatment of angle-closure glaucoma in retinoblastoma
Presenter:
Christina Stathopoulos (Switzerland)
Myelosuppression after intra-arterial chemotherapy for intraocular retinoblastoma with or without prior systemic chemotherapy
Presenter:
Concetta Didomenico (United States)
Impact of choroidal invasion on survival from retinoblastoma using a US national database
Presenter:
Dan S. Gombos (United States)
Clearance of tumor-derived extracellular vesicle heterogeneity in aqueous humor after chemotherapy in retinoblastoma eyes
Presenter:
Deborah Im (United States)
Outcome of silicone vs PMMA orbital implants following minimal manipulation myoconjunctival enucleation in retinoblastoma
Presenter:
Harika Regani (India)
Patient reported outcome measures for retinoblastoma
Presenter:
Helen Dimaras (Canada)
Retinoblastoma tumor DNA testing can decrease residual germline risk in unilateral patients
Presenter:
Hilary Racher (Canada)
When RB met RP
Presenter:
Ido Didi Fabian (Israel)
12:30 p.m. - 01:40 p.m.
Pieter van Slingelandt
Poster session Retinoblastoma 2.2
Moderators:
Nathalie Cassoux (France), Vishal Raval (India) & Mrittika Sen (United States)
Safety-enhanced cataract surgery in children with retinoblastoma: A retrospective case series
Presenter:
Mrittika Sen (United States)
Emerging disease: Spiroplasma - Related uveitis in newborns masquerading anterior retinoblastoma
Presenter:
Nathalie Cassoux (France)
Impact of the Covid-19 pandemic on the care and follow up of retinoblastoma patients in Senegal
Presenter:
Paule Aïda Roth (Senegal)
Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: An initial report
Presenter:
Priya Marathe (United States)
Influence of SARS-CoV-2 pandemic on retinoblastoma presentation – data from an European national reference center
Presenter:
Tobias Kiefer (Germany)
Analysis of referral pattern and pathways of retinoblastoma cases in Ghana
Presenter:
Helen Dimaras (Canada)
Epidemiological and clinical profile of retinoblastoma in Ghana: A baseline national survey
Presenter:
Helen Dimaras (Canada)
Proteome analysis of WERI RB1 and etoposide resistant WERI ETOR retinoblastoma cell lines
Presenter:
Vinodh Kakkassery (Germany)
Macular retinoblastoma: Clinical presentation and treatment outcomes
Presenter:
Vishal Raval (India)
Impact of adjuvant therapy on outcome of massive choroidal invasion of retinoblastoma
Presenter:
Zhao Xun Feng (Canada)
01:40 p.m. - 02:00 p.m.
Johannes Vermeer and Frans van Mieris
S9 J Shields Lecture
01:40 p.m. - 01:45 p.m.
Introduction
Presenter:
Jesse Berry (United States)
01:45 p.m. - 02:00 p.m.
J Shields Lecture
Presenter:
Carol L. Shields (United States)
02:00 p.m. - 03:30 p.m.
Johannes Vermeer and Frans van Mieris
S10 Retinoblastoma: Basic Science and Cases
Moderators:
Jesse Berry (United States), Josephine Dorsman (The Netherlands), Theodora Hadjistilianou (Italy) & Matthew Wilson (United States)
02:00 p.m. - 02:08 p.m.
Proteomics of aqueous humor as a source of disease biomarkers in retinoblastoma
Presenter:
Angela Galardi (Italy)
02:08 p.m. - 02:16 p.m.
What can the aqueous humor liquid biopsy do? Establishing clinical utility of ctDNA analysis for diagnosis, prognosis, and treatment monitoring of retinoblastoma
Presenter:
Jesse Berry (United States)
02:16 p.m. - 02:24 p.m.
Identifying DNA methylation signatures of retinoblastoma via aqueous humor, an ocular liquid biopsy
Presenter:
Liya Xu (United States)
02:24 p.m. - 02:32 p.m.
Retinoblastoma from human stem cell-derived retinal organoids
Presenter:
Matthew Wilson (United States)
02:32 p.m. - 02:40 p.m.
Phase I sustained-release topotecan episcleral plaque (chemoplaque) for retinoblastoma (STEP-RB)
Presenter:
Brenda Gallie (Canada)
02:40 p.m. - 02:48 p.m.
Subretinal grafts of patient-derived retinoblastoma cells in rats reflect different clinical patterns
Presenter:
Denis Malaise (France)
02:48 p.m. - 02:56 p.m.
Can pre-enucleation plasma cfDNA predict which retinoblastoma patients with choroidal invasion will develop metastases?
Presenter:
Jasmine Francis (United States)
02:56 p.m. - 03:04 p.m.
Investigating the aqueous humor and tumor tissue of naïve retinoblastoma eyes in a next‐generation sequencing panel for pediatric malignancies
Presenter:
Indhira Oliveira (Brazil)
03:04 p.m. - 03:06 p.m.
Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy
Presenter:
Jesse Berry (United States)
03:06 p.m. - 03:08 p.m.
Disruption of RB1 exon 5 donor splice site leading to reduced penetrance parent-of-origin effect in two unrelated families
Presenter:
Hilary Racher (Canada)
03:08 p.m. - 03:10 p.m.
Single injection of intracameral chemotherapy for chemo-resistant retinoblastoma with aqueous seeding
Presenter:
Swathi Kaliki (India)
03:10 p.m. - 03:12 p.m.
Unique case of discordant phenotype-genotype analysis in RB: Additional factors at play?
Presenter:
Katherine Paton (Canada)
02:00 p.m. - 03:30 p.m.
Godfried Schalcken
Poster session Uveal Melanoma 2.1 - cont.
Moderators:
Maura Di Nicola (United States), Nanda Horeweg (The Netherlands) & Hatem Krema (Canada)
Post-operative echography for optimization of radiation dosimetry in patients with posterior uveal melanoma treated with plaque brachytherapy
Presenter:
Elaine Binkley (United States)
Gene expression profile and local tumor recurrence of irradiated uveal melanomas
Presenter:
Maura Di Nicola (United States)
Oncological outcome and eye preservation in the first year of a new proton therapy center
Presenter:
Nanda Horeweg (The Netherlands)
Impact of local availability of proton therapy for uveal melanoma on visual outcome
Presenter:
Nanda Horeweg (The Netherlands)
41-gauge fine-needle aspiration biopsy for intraocular tumor
Presenter:
Min Kim (South Korea)
Laser treatment for choroidal melanoma
Presenter:
Abhilasha Maheshwari (United States)
Iris melanoma and sudden death
Presenter:
Scott Oliver (United States)
Clinical utility of preoperative dosimetry for brachytherapy in uveal melanoma
Presenter:
Scott Oliver (United States)
Telomerase gene promoter (TERT) mutation in recurrent uveal melanoma after secondary enucleation revealed by targeted next-generation sequencing
Presenter:
Brittany Perzia (United States)
Can the late effects of fractionated stereotactic radiotherapy for posterior choroidal melanoma be reduced and allow useful vision preservation without compromising metastasis-free survival? A pilot study
Presenter:
Claire Phillips (Australia)
Comparison of MRI-based and conventional measurements for proton beam therapy of uveal melanoma
Presenter:
Berit Verbist (The Netherlands)
Asymmetric loading of Iodine-125 episcleral plaques: Indications and outcomes
Presenter:
Filiberto Altomare (Canada)
Epiphora following specialised teletherapy to medially located ocular tumours
Presenter:
Umiya Harley (United Kingdom)
Accuracy of residual interfraction patient positioning in Ocular Proton Therapy (OPT)
Presenter:
Martijn Hol (The Netherlands)
Inter-observer variability in MR-based target volume delineation of uveal melanoma
Presenter:
Lisa Klaassen (The Netherlands)
3D MRI tumour measurements compared to conventional ultrasound for treatment planning of eye tumours
Presenter:
Lisa Klaassen (The Netherlands)
Biopsies of intraocular tumors - A retrospective analysis from 2017 to 2019
Presenter:
Stefan H. Kreis (Germany)
Germline genetic testing for uveal melanoma: A simplified process
Presenter:
Hatem Krema (Canada)
Demographic and clinical characterization of uveal melanoma patients in a German ophthalmic oncology reference center between 2007 and 2021
Presenter:
Mael Lever (Germany)
02:00 p.m. - 03:30 p.m.
Pieter van Slingelandt
Poster session Uveal Melanoma 2.2 - cont.
Moderators:
Jan-Willem Beenakker (The Netherlands), Hung-Da Chou (Taiwan) & Vicktoria (vicky) Vishnevskia-Dai (Israel)
Amelanotic melanoma presenting as tubercular granuloma
Presenter:
Vishal Raval (India)
Small choroidal melanoma presenting with submacular hemorrhage
Presenter:
Pukhraj Rishi (United States)
MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma
Presenter:
Michael Tang (The Netherlands)
Spontaneous metastasis of uveal melanoma in a mouse orthotopic xenograft model
Presenter:
Raquel Ramos (Spain)
Clinical indications for an MRI for uveal melanoma patients
Presenter:
Jan-Willem Beenakker (The Netherlands)
Using proton beam therapy without preplaced fiducial markers for choroidal melanoma: A preliminary report from a single institute in Asia
Presenter:
Hung-Da Chou (Taiwan)
How do Australian optometrists and ophthalmologists manage choroidal naevi?
Presenter:
Michele C. Madigan (Australia)
I-125 plaque radiation compared with proton radiation for treatment of uveal melanoma
Presenter:
Arman Mashayekhi (United States)
Uveal melanoma surgical approach trough endoresection: A monocentric experience
Presenter:
Cinzia Mazzini (Italy)
Long-term visual outcomes of patients with temporal uveal melanoma treated with proton beam radiotherapy
Presenter:
Sacha Nahon-Esteve (France)
Is ultrasonographic hollowness a prognostic biomarker to identify amelanotic choroidal nevi at risk of transformation into melanoma?
Presenter:
Monica Maria Pagliara (Italy)
Endoresection as primary or secondary management of choroidal melanoma
Presenter:
David Reichstein (United States)
Conditional survival of uveal melanoma using The Cancer Genome Atlas (TCGA) classification (Simplified Version) in 1001 Cases
Presenter:
Carol L. Shields (United States)
Radiation retinopathy: Pilot use of long-acting intravitreal fluocinolone implant
Presenter:
Janani Singaravelu (United States)
Long term clinical outcomes with dedicated proton ocular beam and helium ion radiation for uveal melanoma patients aged 45 and younger
Presenter:
Carly Zako (United States)
Uveal melanoma patients reported outcomes (PROMS)
Presenter:
Vicktoria (vicky) Vishnevskia-Dai (Israel)
Uveal melanoma patient attitudes towards prognostic testing using gene expression profiling
Presenter:
Basil Williams (United States)
Consensus statement for metastatic surveillance of uveal melanomas in Scotland
Presenter:
Vikas Chadha (United Kingdom)
03:30 p.m. - 04:00 p.m.
Coffee break
03:30 p.m. - 04:00 p.m.
Godfried Schalcken
Poster session Retinoblastoma 2.1 - cont.
Moderators:
Helen Dimaras (Canada) & Ido Didi Fabian (Israel)
Identification of novel genes by targeted exome sequencing in retinoblastoma
Presenter:
Bhavna Chawla (India)
Ab interno non filtrating glaucoma surgery for the treatment of angle-closure glaucoma in retinoblastoma
Presenter:
Christina Stathopoulos (Switzerland)
Myelosuppression after intra-arterial chemotherapy for intraocular retinoblastoma with or without prior systemic chemotherapy
Presenter:
Concetta Didomenico (United States)
Impact of choroidal invasion on survival from retinoblastoma using a US national database
Presenter:
Dan S. Gombos (United States)
Clearance of tumor-derived extracellular vesicle heterogeneity in aqueous humor after chemotherapy in retinoblastoma eyes
Presenter:
Deborah Im (United States)
Outcome of silicone vs PMMA orbital implants following minimal manipulation myoconjunctival enucleation in retinoblastoma
Presenter:
Harika Regani (India)
Patient reported outcome measures for retinoblastoma
Presenter:
Helen Dimaras (Canada)
Retinoblastoma tumor DNA testing can decrease residual germline risk in unilateral patients
Presenter:
Hilary Racher (Canada)
When RB met RP
Presenter:
Ido Didi Fabian (Israel)
03:30 p.m. - 04:00 p.m.
Pieter van Slingelandt
Poster session Retinoblastoma 2.2 - cont.
Moderators:
Nathalie Cassoux (France), Vishal Raval (India) & Mrittika Sen (United States)
Safety-enhanced cataract surgery in children with retinoblastoma: A retrospective case series
Presenter:
Mrittika Sen (United States)
Emerging disease: Spiroplasma - Related uveitis in newborns masquerading anterior retinoblastoma
Presenter:
Nathalie Cassoux (France)
Impact of the Covid-19 pandemic on the care and follow up of retinoblastoma patients in Senegal
Presenter:
Paule Aïda Roth (Senegal)
Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: An initial report
Presenter:
Priya Marathe (United States)
Influence of SARS-CoV-2 pandemic on retinoblastoma presentation – data from an European national reference center
Presenter:
Tobias Kiefer (Germany)
Analysis of referral pattern and pathways of retinoblastoma cases in Ghana
Presenter:
Helen Dimaras (Canada)
Epidemiological and clinical profile of retinoblastoma in Ghana: A baseline national survey
Presenter:
Helen Dimaras (Canada)
Proteome analysis of WERI RB1 and etoposide resistant WERI ETOR retinoblastoma cell lines
Presenter:
Vinodh Kakkassery (Germany)
Macular retinoblastoma: Clinical presentation and treatment outcomes
Presenter:
Vishal Raval (India)
Impact of adjuvant therapy on outcome of massive choroidal invasion of retinoblastoma
Presenter:
Zhao Xun Feng (Canada)
04:00 p.m. - 05:00 p.m.
Johannes Vermeer and Frans van Mieris
S11 Retinoblastoma: International Studies
Moderators:
Laurence Desjardins (France), Ido Didi Fabian (Israel), Maria Manquez Hatta (Chile) & Prithvi Mruthyunjaya (United States)
04:00 p.m. - 04:08 p.m.
Global retinoblastoma outcome study: Analysis of 4,064 patients from 149 countries
Presenter:
Ido Didi Fabian (Israel)
04:08 p.m. - 04:16 p.m.
Artificial intelligence and machine learning in ocular oncology: Retinoblastoma
Presenter:
Swathi Kaliki (India)
04:16 p.m. - 04:24 p.m.
How telemedicine and centralized care changed the natural history of retinoblastoma in a developing country: Analysis of 478 patients treated over 17 years
Presenter:
Yacoub Yousef (Jordan)
04:24 p.m. - 04:32 p.m.
Advanced unilateral retinoblastoma requiring enucleation: European standard clinical practice guidelines
Presenter:
Alexandre Matet (France)
04:32 p.m. - 04:40 p.m.
A global online retinoblastoma academy
Presenter:
Matthew Wilson (United States)
04:40 p.m. - 04:48 p.m.
Leukocoria detector app - Highs & lows on implementation in a developing country
Presenter:
Maria Manquez Hatta (Chile)
04:48 p.m. - 04:56 p.m.
Programme to improve retinoblastoma care in subsaharan Africa
Presenter:
Laurence Desjardins (France)
05:00 p.m. - 07:00 p.m.
Boat tour through the Leiden canals
07:00 p.m. - 08:00 p.m.
Industry Reception