Program

Program at a glance

The ISOO 2022 Congress will take place from Friday, June 17 - Tuesday, June 21, 2022 in Leiden, The Netherlands. Please click on the image below for the full program at a glance. An overview of the sessions can be found below.

Friday, June 17, 2022

08:59 a.m. - 10:30 a.m.

Johannes Vermeer and Frans van Mieris

S1 Scientific Collaborations: Horizon2020 CURE UM

Moderators: Niels Brouwer (The Netherlands), Martyna Elas (Poland), B. Ewa Jagalska (The Netherlands) & Sergio Roman-Roman (France)

08:59 a.m. - 09:00 a.m.

Introducing CURE UM

Presenter: Sergio Roman-Roman (France)

09:00 a.m. - 09:08 a.m.

Protein tyrosine kinase activity in primary uveal melanoma is associated with the presence of tumour-infiltrating leukocytes

Presenter: Annemijn Wierenga (The Netherlands)

09:08 a.m. - 09:16 a.m.

Novel therapies for uveal melanoma

Presenter: Kseniya Glinkina (The Netherlands)

09:16 a.m. - 09:24 a.m.

Tumor-infiltrating T cells can successfully be expanded from primary uveal melanoma after separation from their tumor environment

Presenter: Gülcin Gezgin (The Netherlands)

09:24 a.m. - 09:32 a.m.

Characterization of immune cell infiltrates and immune checkpoints in primary UM and liver metastases

Presenter: Raymond Barnhill (France)

09:32 a.m. - 09:40 a.m.

The high-risk replacement histopathologic growth pattern in UM liver metastases

Presenter: Raymond Barnhill (France)

09:40 a.m. - 09:48 a.m.

Tumour pigmentation and chromosome 3 are related in uveal melanoma

Presenter: Maria Chiara Gelmi (The Netherlands)

09:48 a.m. - 09:56 a.m.

Ferroptosis inhibition by melanin promotes metastatic colonization of melanoma cells

Presenter: B. Ewa Jagalska (The Netherlands)

09:56 a.m. - 10:04 a.m.

Melanization of human UM tumors affects their metastasizing in mice

Presenter: Małgorzata Szczygieł (Poland)

10:04 a.m. - 10:12 a.m.

Uveal melanoma cell lines grown as 3D tumor spheroids

Presenter: Anna Kozińska (Poland)

10:12 a.m. - 10:20 a.m.

Vitreous fluid as a novel liquid biopsy for primary uveal melanoma

Presenter: Rogier J. Nell (The Netherlands)

10:20 a.m. - 10:28 a.m.

Ocular toxicity in uveal melanoma patients treated in the first year of a new proton therapy center

Presenter: Marina Marinkovic (The Netherlands)

10:30 a.m. - 11:00 a.m.

Coffee break

11:00 a.m. - 12:30 p.m.

Johannes Vermeer and Frans van Mieris

S2 International Collaborations in Ocular Oncology

Moderators: Rana'a Al Jamal (Finland), Brenda Gallie (Canada), Rogier J. Nell (The Netherlands) & Vicktoria (vicky) Vishnevskia-Dai (Israel)

11:00 a.m. - 11:08 a.m.

PRIMA (PRegnancy In uveal Melanoma Analysis) study ‎- A European OOG MultiCenter study

Presenter: Shahar Frenkel (Israel)

11:08 a.m. - 11:16 a.m.

Clinical phenotype of germline BAP1 mutation mmong pediatric uveal melanomas

Presenter: Rana'a Al Jamal (Finland)

11:16 a.m. - 11:24 a.m.

Nevus of Ota: Suggestion for new ocular classification

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

11:24 a.m. - 11:32 a.m.

Capturing uveal melanoma (UM) global practice patterns and clinical outcomes in the collaborative ocular melanoma natural history (OMNi; NCT04588662) study

Presenter: Richard Carvajal (United States)

11:32 a.m. - 11:40 a.m.

Euracan collaboration

Presenters: Ellen Kapiteijn (The Netherlands) & Sophie Piperno-Neumann (France)

11:40 a.m. - 11:48 a.m.

An integrative, prospective clinical and tissue database for uveal melanoma

Presenter: Lauren Dalvin (United States)

11:48 a.m. - 11:56 a.m.

VISION (Virtual Information System to Improve Outcomes and Networks) - Advancing Ocular Melanoma (OM) research through patient powered data collection

Presenter: Sara Selig (United States)

11:56 a.m. - 12:04 p.m.

Developing an ocular oncology fellowship program

Presenter: Hatem Krema (Canada)

12:04 p.m. - 12:12 p.m.

Stage IV uveal melanoma: Pooled data from of an international registry

Presenter: Gaurav Garg (India)

12:12 p.m. - 12:20 p.m.

Update on international Rb database

Presenter: Brenda Gallie (Canada)

12:20 p.m. - 12:28 p.m.

High-level MYCN-amplified RB1-proficient retinoblastoma tumors retain distinct molecular signatures

Presenter: Josephine Dorsman (The Netherlands)

EURbG Business Meeting

11:00 a.m. - 12:30 p.m.

Willem van de Velde

Rb FAM (parallel session, members only)

12:30 p.m. - 01:30 p.m.

Lunch break

01:30 p.m. - 02:00 p.m.

Johannes Vermeer and Frans van Mieris

S3 Lex van der Eb Lecture

01:30 p.m. - 01:40 p.m.

Development Leiden Bio Science Park

Presenter: Bart van Zijll Langhout (The Netherlands)

01:40 p.m. - 02:00 p.m.

Lex van der Eb Lecture

Presenter: J. William Harbour (United States)

Moderator: Martine Jager (The Netherlands)

EURbG Business Meeting

01:30 p.m. - 03:30 p.m.

Willem van de Velde

EURbG Business Meeting (parallel session, members only)

02:00 p.m. - 03:30 p.m.

Johannes Vermeer and Frans van Mieris

S4 Genetics and Epigenetics in Oncology

Moderators: Shahar Frenkel (Israel), J. William Harbour (United States), Emine Kiliç (The Netherlands) & Marc-Henri Stern (France)

02:00 p.m. - 02:10 p.m.

Aging and epigenetic changes

Presenter: Bruce Ksander (United States)

02:10 p.m. - 02:18 p.m.

Genetics and prognostic value of TERT promoter mutations in conjunctival melanoma

Presenter: Natasha van Poppelen (The Netherlands)

02:18 p.m. - 02:26 p.m.

Contribution of MYC copy number gain and mutations in tumor suppressor genes to the oncogenesis of ocular adnexal sebaceous carcinomas

Presenter: Cornelia Peterson (United States)

02:26 p.m. - 02:34 p.m.

Primary UM display intratumoral heterogeneity; HES6, a driver of metastatic disease

Presenter: Corine Bertolotto (France)

02:34 p.m. - 02:42 p.m.

Disease-specific mortality among patients with local recurrence from uveal melanoma is primarily driven by chromosomes 3 and 8q

Presenter: Mette Bagger (Denmark)

02:42 p.m. - 02:50 p.m.

Chromosome 3 and 8q aberrations in uveal melanoma show greater impact on survival in patients with light iris versus dark iris color

Presenter: Martine Jager (The Netherlands)

02:50 p.m. - 02:58 p.m.

Different pigmentation risk loci for high-risk, monosomy 3 and low-risk, disomy 3 uveal melanomas

Presenter: Marc-Henri Stern (France)

02:58 p.m. - 03:06 p.m.

Impact of PRAME status on Gene Expression Profile to predict metastasis in UM: interim analysis of the COOG2

Presenter: Alison Skalet (United States)

03:06 p.m. - 03:14 p.m.

Leveraging single cell genomics and epigenomics to provide accurate prognostication for patients with uveal melanoma

Presenter: Mathieu Bakhoum (United States)

03:14 p.m. - 03:22 p.m.

Aqueous humor-derived MYD88 L265P mutation analysis in vitreoretinal lymphoma: A potential less-invasive method for diagnosis and treatment response assessment

Presenter: Hakan Demirci (United States)

03:22 p.m. - 03:30 p.m.

Ocular adnexal large B-cell lymphoma: Prevalence and prognostic value of MYD88 and CD79B mutations, double-hit lymphoma, and double-expressor phenotype

Presenter: Marina Knudsen Kirkegaard (Denmark)

03:30 p.m. - 04:00 p.m.

Coffee break

04:00 p.m. - 05:00 p.m.

Johannes Vermeer and Frans van Mieris

S5 Immunology in Ocular Oncology

Moderators: Marlana Orloff (United States), Sophie Piperno-Neumann (France), Manuel Rodrigues (France) & Robert Verdijk (The Netherlands)

04:00 p.m. - 04:08 p.m.

Combining Checkpoint Inhibitors and liver perfusion

Presenter: Thais Tong (The Netherlands)

04:08 p.m. - 04:16 p.m.

PERIO-01: A phase 1/1b trial of hepatic arterial infusion of SD-101 +/- checkpoint inhibition in metastatic uveal melanoma using pressure-enabled drug delivery

Presenter: Sapna Patel (United States)

04:16 p.m. - 04:24 p.m.

Macrophage Inhibitory Factor (MIF) Inhibition as a novel adjuvant treatment strategy for high risk uveal melanoma (UM)

Presenter: Alex Rai (United States)

04:24 p.m. - 04:32 p.m.

Predominance of CD8+ T cell infiltration is most pronounced in high-risk primary uveal melanoma

Presenter: Kalijn Bol (The Netherlands)

04:32 p.m. - 04:40 p.m.

MBD4 deficiency is predictive of response to immune checkpoint inhibitors in metastatic uveal melanoma patients

Presenter: Manuel Rodrigues (France)

04:40 p.m. - 04:48 p.m.

Tebentafusp in UM

Presenter: Sophie Piperno-Neumann (France)

04:48 p.m. - 04:56 p.m.

Metastatic uveal melanoma patients with long term survival after tebentafusp

Presenter: Marlana Orloff (United States)

EURbG Business Meeting

04:00 p.m. - 05:00 p.m.

Willem van de Velde

EURbG Business Meeting (parallel session, members only)

05:00 p.m. - 07:00 p.m.

Golden Dome Building - LUMC Building 3

Welcome Reception

Saturday, June 18, 2022

08:00 a.m. - 08:45 a.m.

Johannes Vermeer and Frans van Mieris

Newcomer Session: Introduction to the ISOO and History of Ocular Oncology

08:00 a.m. - 08:02 a.m.

Welcome

Presenter: Dan S. Gombos (United States)

08:02 a.m. - 08:15 a.m.

History of ISOO

Presenter: Koby Pe'er (Israel)

08:15 a.m. - 08:30 a.m.

Historic evelopments in Uveal Melanoma

Presenter: Bertil Damato (United Kingdom/Sweden)

08:30 a.m. - 08:45 a.m.

Historic developments in Retinoblastoma

Presenter: Francis Munier (Switzerland)

08:00 a.m. - 08:50 a.m.

Willem van de Velde

Coffee with Experts - Imaging of Rb, Uveal Melanoma, Eyelids

08:00 a.m. - 08:15 a.m.

Imaging in retinoblastoma

Presenter: Pim de Graaf (The Netherlands)

08:15 a.m. - 08:30 a.m.

Imaging in uveal melanoma

Presenter: Jan-Willem Beenakker (The Netherlands)

08:30 a.m. - 08:40 a.m.

MR and CT imaging of the normal eyelid and its application in eyelid tumors

Presenter: Teresa Gonçalves Ferreira (The Netherlands)

08:40 a.m. - 08:50 a.m.

Ultrasound guidance of plaque placement for choroidal melanoma

Presenter: Brian Marr (United States)

08:00 a.m. - 09:00 a.m.

Jan Steen

Poster session Retinoblastoma 1.1

Moderators: Eva Biewald (Germany), Emine Kiliç (The Netherlands) & Ankit Singh Tomar (India)

Global retinoblastoma treatment outcomes: Association with national income level

Presenter: Ankit Singh Tomar (India)

Clinical features in advanced retinoblastoma: High risk pathology and metastatic death

Presenter: Ankit Singh Tomar (India)

Combined intravitreal chemotherapy with carboplatin plus melphalan for management of vitreous seeding in retinoblastoma

Presenter: Babak Masoomian (Iran)

Intravitreal carboplatin as salvage treatment for progressive vitreous disease in retinoblastoma: A phase I clinical trial

Presenter: Benjamin King (United States)

Intravitreal chemotherapy eligibility and ocular survival for advanced retinoblastoma

Presenter: Benjamin King (United States)

Correlation of neuroimaging and histopathologic risk factors of advanced group E retinoblastoma

Presenter: Eva Biewald (Germany)

Bilateral retinoblastoma: The challenge of managment in sub-Saharan Africa support unit

Presenter: Fatoumata Sylla (Mali)

08:00 a.m. - 09:00 a.m.

Godfried Schalcken

Poster session Retinoblastoma 1.2

Moderators: Nathalie Cassoux (France), M. Ashwin Reddy (United Kingdom) & Luiz Teixeira (Brazil)

Outcomes of tandem intravitreal chemotherapy for refractory vitreous seeds in retinoblastoma

Presenter: Gaurav Garg (India)

Association of RB1 rs9568036 and CDKN1A rs1801270 polymorphisms to retinoblastoma susceptibility

Presenter: Golnaz Khakpour (Iran)

Ruthenium plaque brachytherapy in the current era of retinoblastoma treatment

Presenter: Guy Negretti (United Kingdom)

Understanding the age of the tumour occurrences in familial retinoblastoma in a single-centre retinoblastoma service

Presenter: Jessica Walker (United Kingdom)

Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma

Presenter: Jiayan Fan (China)

Clinical presentation and outcome of retinoblastoma in older children

Presenter: Luiz Teixeira (Brazil)

The impact of children with pseudoretinoblastoma presenting to a retinoblastoma unit

Presenter: M. Ashwin Reddy (United Kingdom)

Central nervous system invasion in retinoblastoma – A case report

Presenter: Maria Teresa Bonanomi (Brazil)

08:00 a.m. - 09:00 a.m.

Pieter van Slingelandt

Poster session Retinoblastoma 1.3

Moderators: Machteld Bosscha (The Netherlands), Carol L. Shields (United States) & Matthew Wilson (United States)

Extending the reach: The impact of orbis Cybersight over on global retinoblastoma over two decades

Presenter: Matthew Wilson (United States)

Familial retinoblastoma: Variations in clinical presentation and management based on maternal versus paternal inheritance

Presenter: Carol L. Shields (United States)

Correlation of clinical and histopathological risk factors and the role of adjuvant therapy in the era of secondary enucleation for retinoblastoma

Presenter: Rolika Bansal (India)

Differences in childhood growth parameters between patients with sporadic and heritable retinoblastoma

Presenter: Roxana Hicks (United States)

Radiotherapy after high dose chemotherapy and stem cell rescue (HDC-ASCT) may improve survival in patients with CNS retinoblastoma – A single center experience

Presenter: Ira Dunkel (United States)

Formation of a global retinoblastoma advisory group

Presenter: Matthew Wilson (United States)

Eye preservation therapy for unilateral retinoblastoma

Presenter: Shigenobu Suzuki (Japan)

Chromosome 6p amplification detected in blood cell-free DNA in advanced retinoblastoma

Presenter: Shreya Sirivolu (United States)

Histopathologic observations of intra arterial chemotherapy in a xenograft rabbit retinoblastoma model

Presenter: Stephen Chen (United States)

09:00 a.m. - 10:30 a.m.

Johannes Vermeer and Frans van Mieris

S6 Retinoblastoma

Moderators: Jasmine Francis (United States), Dan S. Gombos (United States), Annette Moll (The Netherlands) & Carol L. Shields (United States)

09:00 a.m. - 09:08 a.m.

Tenfold increased risk for subsequent primary malignancies in survivors of heritable retinoblastoma; an update of the Dutch nationwide cohort

Presenter: Milo van Hoefen Wijsard (The Netherlands)

09:08 a.m. - 09:16 a.m.

Lack of complete response pre-transplant is not associated with inferior overall survival for stage 4a metastatic retinoblastoma

Presenter: Ira Dunkel (United States)

09:16 a.m. - 09:24 a.m.

Tylectomy for salvage of eyes with retinoblastoma

Presenter: Zhao Xun Feng (Canada)

09:24 a.m. - 09:32 a.m.

Comparison of intravenous and intraarterial chemotherapy: Results from 1080 patients from 54 countries

Presenter: Andrew Stacey (United States)

09:32 a.m. - 09:40 a.m.

Aqueous seeding in retinoblastoma: Classification and clinicopathological correlation

Presenter: Swathi Kaliki (India)

09:40 a.m. - 09:48 a.m.

Impact of chemotherapy on secondary primary malignancies in patients with germline retinoblastoma

Presenter: Dan S. Gombos (United States)

09:48 a.m. - 09:56 a.m.

Eye globe salvage in advanced group E retinoblastoma

Presenter: Theodora Hadjistilianou (Italy)

09:56 a.m. - 10:04 a.m.

Single-center, long-term, real-world outcomes of intravenous and/or intra-arterial chemotherapy for retinoblastoma - Does it last to 10 or 20 years?

Presenter: Carol L. Shields (United States)

10:04 a.m. - 10:12 a.m.

At what age could screening of children at risk for familial retinoblastoma be stopped?

Presenter: Annette Moll (The Netherlands)

10:12 a.m. - 10:20 a.m.

In vivo imaging of anterior segment invasion in retinoblastoma: Description of the invasion profiles and implications for therapeutic decision-making

Presenter: Francis Munier (Switzerland)

10:20 a.m. - 10:28 a.m.

Primary orbital retinoblastoma - Long-term outcome of Intensive Multimodal Treatment Protocol (IMTP)

Presenter: Fairooz P Manjandavida (India)

09:00 a.m. - 10:30 a.m.

Jan Steen

Poster session Uveal Melanoma 1.1

Moderators: Nikos Bechrakis (Germany), Amy Schefler (United States) & Basil Williams (United States)

Tissue glue adhesion for plaque brachytherapy of uveal melanoma in humans, an initial experience

Presenter: Kushal Agrawal (United States)

Preferentially Expressed Antigen in Melanoma (PRAME) immunohistochemistry labeling in uveal melanomas

Presenter: Saman Ahmadian (United States)

106-Ruthenium brachytherapy in large uveal melanoma

Presenter: Nikos Bechrakis (Germany)

Potential of aqueous humor as a liquid biopsy for uveal melanoma

Presenter: Jesse Berry (United States)

Staged brachytherapy: A novel approach for large uveal melanoma

Presenter: Maria Bretana (United States)

Combined GEP and PRAME testing creates high-risk stratification for half of uveal melanoma patients

Presenter: Peter Hovland (United States)

Randomized trial of treat-and extend intravitreal aflibercept for radiation retinopathy: One year outcomes

Presenter: Amy Schefler (United States)

Macrophage migration-inhibitory factor (MIF): Expression in high risk UM

Presenter: Zahra Souri (Iran)

Evaluation of outcomes following implementation of a nurse-led oncology clinic during COVID-19

Presenter: Osman Younus (United Kingdom)

Survey of fine needle aspiration biopsy techniques for intraocular tumors

Presenter: Basil Williams (United States)

Cytogenetic evidence of the higher metastatic risk in the ciliary body involved uveal melanoma

Presenter: An-Ning Chao (Taiwan)

09:00 a.m. - 10:30 a.m.

Godfried Schalcken

Poster session Uveal Melanoma 1.2

Moderators: Marem Chionkhumi Christy (India), Martyna Elas (Poland) & Gre Luyten (The Netherlands)

Melanocytoma co-existing in choroidal melanoma

Presenter: Marem Chionkhumi Christy (India)

Uveal melanoma prognostication: GEP vs NGS

Presenter: Jacquelyn Davanzo (United States)

Outpatient ocular brachytherapy

Presenter: Richard Jennelle (United States)

Conformal plaque brachytherapy outcomes for peripapillary choroidal melanoma

Presenter: Emily Liao (Canada)

Long term follow-up of circumscribed iris melanomas treated by proton beam therapy

Presenter: Livia Lumbroso-le Rouic (France)

The impact of the COVID-19 pandemic on diagnosis and treatment of choroidal melanoma patients in the Netherlands

Presenter: Gre Luyten (The Netherlands)

Uveal melanoma metastasis to the contralateral eye structures: A retrospective comparative analysis of 13 consecutive patients

Presenter: Babak Masoomian (Iran)

Post-enucleation radiotherapy for uveal melanoma with extrascleral extension

Presenter: Deep Sarode (United Kingdom)

Next generation preclinical models of uveal melanoma

Presenter: Małgorzata Szczygieł (Poland)

Long-term results in the treatment of radiation-induced maculopathy with Fluocinolone Acetonide

Presenter: Lena Zimmermann (Germany)

Patient satisfaction with teleophthalmology in ocular oncology

Presenter: Paige Campbell (Canada)

09:00 a.m. - 10:30 a.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 1.3

Moderators: Niels Brouwer (The Netherlands), Jared Ebert (United States) & Raffaele Parrozzani (Italy)

Gene expression profile class changes on interval biopsies of choroidal melanomas

Presenter: Jared Ebert (United States)

Proton beam radiotherapy treatment of iris melanoma

Presenter: Katharina Eibenberger (United Kingdom)

Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations in uveal melanoma

Presenter: Rosaria Gangemi (Italy)

Key clinical concepts from multi-institutional experience with dedicated fixed low-energy proton ocular beamlines

Presenter: Kavita Mishra (United States)

Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma

Presenter: Kavita Mishra (United States)

Ruthenium-106 plaque radiotherapy for uveal melanoma: Analysis of tumor thickness and location on anatomical and functional results

Presenter: Masood Naseripour (Iran)

Hyperreflective Retinal Foci Detected by SD-OCT anticipate radiation-induced macular edema

Presenter: Raffaele Parrozzani (Italy)

Radiation dose correlation to radiation induced ocular complications

Presenter: Ekaterina Sokolenko (Germany)

Uveal melanoma: Evidence of cure

Presenter: Emily Zabor (United States)

Diagnosis of small choroidal melanoma : A machine learning based prediction model

Presenter: Emily Zabor (United States)

10:30 a.m. - 11:00 a.m.

Coffee break

10:30 a.m. - 11:00 a.m.

Jan Steen

Poster session Retinoblastoma 1.1 - cont.

Moderators: Eva Biewald (Germany), Emine Kiliç (The Netherlands) & Ankit Singh Tomar (India)

Global retinoblastoma treatment outcomes: Association with national income level

Presenter: Ankit Singh Tomar (India)

Clinical features in advanced retinoblastoma: High risk pathology and metastatic death

Presenter: Ankit Singh Tomar (India)

Combined intravitreal chemotherapy with carboplatin plus melphalan for management of vitreous seeding in retinoblastoma

Presenter: Babak Masoomian (Iran)

Intravitreal carboplatin as salvage treatment for progressive vitreous disease in retinoblastoma: A phase I clinical trial

Presenter: Benjamin King (United States)

Intravitreal chemotherapy eligibility and ocular survival for advanced retinoblastoma

Presenter: Benjamin King (United States)

Correlation of neuroimaging and histopathologic risk factors of advanced group E retinoblastoma

Presenter: Eva Biewald (Germany)

Bilateral retinoblastoma: The challenge of managment in sub-Saharan Africa support unit

Presenter: Fatoumata Sylla (Mali)

10:30 a.m. - 11:00 a.m.

Godfried Schalcken

Poster session Retinoblastoma 1.2 - cont.

Moderators: Nathalie Cassoux (France), M. Ashwin Reddy (United Kingdom) & Luiz Teixeira (Brazil)

Outcomes of tandem intravitreal chemotherapy for refractory vitreous seeds in retinoblastoma

Presenter: Gaurav Garg (India)

Association of RB1 rs9568036 and CDKN1A rs1801270 polymorphisms to retinoblastoma susceptibility

Presenter: Golnaz Khakpour (Iran)

Ruthenium plaque brachytherapy in the current era of retinoblastoma treatment

Presenter: Guy Negretti (United Kingdom)

Understanding the age of the tumour occurrences in familial retinoblastoma in a single-centre retinoblastoma service

Presenter: Jessica Walker (United Kingdom)

Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma

Presenter: Jiayan Fan (China)

Clinical presentation and outcome of retinoblastoma in older children

Presenter: Luiz Teixeira (Brazil)

The impact of children with pseudoretinoblastoma presenting to a retinoblastoma unit

Presenter: M. Ashwin Reddy (United Kingdom)

Central nervous system invasion in retinoblastoma – A case report

Presenter: Maria Teresa Bonanomi (Brazil)

10:30 a.m. - 11:00 a.m.

Pieter van Slingelandt

Poster session Retinoblastoma 1.3 - cont.

Moderators: Machteld Bosscha (The Netherlands), Carol L. Shields (United States) & Matthew Wilson (United States)

Extending the reach: The impact of orbis Cybersight over on global retinoblastoma over two decades

Presenter: Matthew Wilson (United States)

Familial retinoblastoma: Variations in clinical presentation and management based on maternal versus paternal inheritance

Presenter: Carol L. Shields (United States)

Correlation of clinical and histopathological risk factors and the role of adjuvant therapy in the era of secondary enucleation for retinoblastoma

Presenter: Rolika Bansal (India)

Differences in childhood growth parameters between patients with sporadic and heritable retinoblastoma

Presenter: Roxana Hicks (United States)

Radiotherapy after high dose chemotherapy and stem cell rescue (HDC-ASCT) may improve survival in patients with CNS retinoblastoma – A single center experience

Presenter: Ira Dunkel (United States)

Formation of a global retinoblastoma advisory group

Presenter: Sarah Huemmer (United States)

Eye preservation therapy for unilateral retinoblastoma

Presenter: Shigenobu Suzuki (Japan)

Chromosome 6p amplification detected in blood cell-free DNA in advanced retinoblastoma

Presenter: Shreya Sirivolu (United States)

Histopathologic observations of intra arterial chemotherapy in a xenograft rabbit retinoblastoma model

Presenter: Stephen Chen (United States)

11:00 a.m. - 11:40 a.m.

Johannes Vermeer and Frans van Mieris

S7 Opening Ceremony

11:00 a.m. - 11:03 a.m.

President ISOO Congress

Presenter: Martine Jager (The Netherlands)

11:03 a.m. - 11:06 a.m.

Chairman Ophthalmology Department Leiden

Presenter: Gre Luyten (The Netherlands)

11:06 a.m. - 11:09 a.m.

ISOO Congres Program

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

11:09 a.m. - 11:12 a.m.

President EURbG

Presenter: Maya Beck-Popovic (Switzerland)

11:12 a.m. - 11:15 a.m.

President OOG

Presenter: Steffen Heegaard (Denmark)

11:15 a.m. - 11:25 a.m.

President ARVO

Presenter: Hans Grossniklaus (United States)

11:25 a.m. - 11:30 a.m.

President ISOO

Presenter: Dan S. Gombos (United States)

11:30 a.m. - 11:32 a.m.

President ISOO Congress

Presenter: Martine Jager (The Netherlands)

11:32 a.m. - 11:42 a.m.

Closing the health gap: the role of diversity in Ophthalmology

Presenter: Basil Williams (United States)

11:42 a.m. - 11:52 a.m.

Women in medicine in Ancient Greece: legendary figures between myths and history

Presenter: Theodora Hadjistilianou (Italy)

11:52 a.m. - 12:02 p.m.

Women in Ophthalmic Oncology

Presenter: Carol L. Shields (United States)

12:02 p.m. - 12:12 p.m.

Victoria Lendrum Cohen Award

Presenter: Nick Rapley (United Kingdom)

11:00 a.m. - 12:30 p.m.

Jan Steen

Poster session Uveal Melanoma 1.1 - cont.

Moderators: Nikos Bechrakis (Germany), Amy Schefler (United States) & Basil Williams (United States)

Tissue glue adhesion for plaque brachytherapy of uveal melanoma in humans, an initial experience

Presenter: Kushal Agrawal (United States)

Preferentially Expressed Antigen in Melanoma (PRAME) immunohistochemistry labeling in uveal melanomas

Presenter: Saman Ahmadian (United States)

106-Ruthenium brachytherapy in large uveal melanoma

Presenter: Nikos Bechrakis (Germany)

Potential of aqueous humor as a liquid biopsy for uveal melanoma

Presenter: Jesse Berry (United States)

Staged brachytherapy: A novel approach for large uveal melanoma

Presenter: Maria Bretana (United States)

Combined GEP and PRAME testing creates high-risk stratification for half of uveal melanoma patients

Presenter: Peter Hovland (United States)

Randomized trial of treat-and extend intravitreal aflibercept for radiation retinopathy: One year outcomes

Presenter: Amy Schefler (United States)

Macrophage migration-inhibitory factor (MIF): Expression in high risk UM

Presenter: Zahra Souri (Iran)

Evaluation of outcomes following implementation of a nurse-led oncology clinic during COVID-19

Presenter: Osman Younus (United Kingdom)

Survey of fine needle aspiration biopsy techniques for intraocular tumors

Presenter: Basil Williams (United States)

Cytogenetic evidence of the higher metastatic risk in the ciliary body involved uveal melanoma

Presenter: An-Ning Chao (Taiwan)

11:00 a.m. - 12:30 p.m.

Godfried Schalcken

Poster session Uveal Melanoma 1.2 - cont.

Moderators: Marem Chionkhumi Christy (India), Martyna Elas (Poland) & Gre Luyten (The Netherlands)

Melanocytoma co-existing in choroidal melanoma

Presenter: Marem Chionkhumi Christy (India)

Uveal melanoma prognostication: GEP vs NGS

Presenter: Jacquelyn Davanzo (United States)

Outpatient ocular brachytherapy

Presenter: Richard Jennelle (United States)

Conformal plaque brachytherapy outcomes for peripapillary choroidal melanoma

Presenter: Emily Liao (Canada)

Long term follow-up of circumscribed iris melanomas treated by proton beam therapy

Presenter: Livia Lumbroso-le Rouic (France)

The impact of the COVID-19 pandemic on diagnosis and treatment of choroidal melanoma patients in the Netherlands

Presenter: Gre Luyten (The Netherlands)

Uveal melanoma metastasis to the contralateral eye structures: A retrospective comparative analysis of 13 consecutive patients

Presenter: Babak Masoomian (Iran)

Post-enucleation radiotherapy for uveal melanoma with extrascleral extension

Presenter: Deep Sarode (United Kingdom)

Next generation preclinical models of uveal melanoma

Presenter: Małgorzata Szczygieł (Poland)

Long-term results in the treatment of radiation-induced maculopathy with Fluocinolone Acetonide

Presenter: Lena Zimmermann (Germany)

Patient satisfaction with teleophthalmology in ocular oncology

Presenter: Paige Campbell (Canada)

11:00 a.m. - 12:30 p.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 1.3 - cont.

Moderators: Niels Brouwer (The Netherlands), Jared Ebert (United States) & Raffaele Parrozzani (Italy)

Gene expression profile class changes on interval biopsies of choroidal melanomas

Presenter: Jared Ebert (United States)

Proton beam radiotherapy treatment of iris melanoma

Presenter: Katharina Eibenberger (United Kingdom)

Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations in uveal melanoma

Presenter: Rosaria Gangemi (Italy)

Key clinical concepts from multi-institutional experience with dedicated fixed low-energy proton ocular beamlines

Presenter: Kavita Mishra (United States)

Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma

Presenter: Kavita Mishra (United States)

Ruthenium-106 plaque radiotherapy for uveal melanoma: Analysis of tumor thickness and location on anatomical and functional results

Presenter: Masood Naseripour (Iran)

Hyperreflective Retinal Foci Detected by SD-OCT anticipate radiation-induced macular edema

Presenter: Raffaele Parrozzani (Italy)

Radiation dose correlation to radiation induced ocular complications

Presenter: Ekaterina Sokolenko (Germany)

Uveal melanoma: Evidence of cure

Presenter: Emily Zabor (United States)

Diagnosis of small choroidal melanoma : A machine learning based prediction model

Presenter: Emily Zabor (United States)

12:30 p.m. - 01:40 p.m.

Lunch

12:30 p.m. - 01:40 p.m.

Jan Steen

YOO Lunch

12:30 p.m. - 01:40 p.m.

Panel discussion on post-fellowship and early career challenges

Presenters: Mary Beth Aronow (United States), Ido Didi Fabian (Israel), Swathi Kaliki (India), Andrew Stacey (United States) & Christina Stathopoulos (Switzerland)

12:30 p.m. - 01:40 p.m.

Godfried Schalcken

Poster session Retinoblastoma 2.1

Moderators: Helen Dimaras (Canada) & Ido Didi Fabian (Israel)

Identification of novel genes by targeted exome sequencing in retinoblastoma

Presenter: Bhavna Chawla (India)

Ab interno non filtrating glaucoma surgery for the treatment of angle-closure glaucoma in retinoblastoma

Presenter: Christina Stathopoulos (Switzerland)

Myelosuppression after intra-arterial chemotherapy for intraocular retinoblastoma with or without prior systemic chemotherapy

Presenter: Concetta Didomenico (United States)

Impact of choroidal invasion on survival from retinoblastoma using a US national database

Presenter: Dan S. Gombos (United States)

Clearance of tumor-derived extracellular vesicle heterogeneity in aqueous humor after chemotherapy in retinoblastoma eyes

Presenter: Deborah Im (United States)

Outcome of silicone vs PMMA orbital implants following minimal manipulation myoconjunctival enucleation in retinoblastoma

Presenter: Harika Regani (India)

Patient reported outcome measures for retinoblastoma

Presenter: Helen Dimaras (Canada)

Retinoblastoma tumor DNA testing can decrease residual germline risk in unilateral patients

Presenter: Hilary Racher (Canada)

When RB met RP

Presenter: Ido Didi Fabian (Israel)

12:30 p.m. - 01:40 p.m.

Pieter van Slingelandt

Poster session Retinoblastoma 2.2

Moderators: Nathalie Cassoux (France), Vishal Raval (India) & Mrittika Sen (United States)

Safety-enhanced cataract surgery in children with retinoblastoma: A retrospective case series

Presenter: Mrittika Sen (United States)

Emerging disease: Spiroplasma - Related uveitis in newborns masquerading anterior retinoblastoma

Presenter: Nathalie Cassoux (France)

Impact of the Covid-19 pandemic on the care and follow up of retinoblastoma patients in Senegal

Presenter: Paule Aïda Roth (Senegal)

Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: An initial report

Presenter: Priya Marathe (United States)

Influence of SARS-CoV-2 pandemic on retinoblastoma presentation – data from an European national reference center

Presenter: Tobias Kiefer (Germany)

Analysis of referral pattern and pathways of retinoblastoma cases in Ghana

Presenter: Helen Dimaras (Canada)

Epidemiological and clinical profile of retinoblastoma in Ghana: A baseline national survey

Presenter: Helen Dimaras (Canada)

Proteome analysis of WERI RB1 and etoposide resistant WERI ETOR retinoblastoma cell lines

Presenter: Vinodh Kakkassery (Germany)

Macular retinoblastoma: Clinical presentation and treatment outcomes

Presenter: Vishal Raval (India)

Impact of adjuvant therapy on outcome of massive choroidal invasion of retinoblastoma

Presenter: Zhao Xun Feng (Canada)

01:40 p.m. - 02:00 p.m.

Johannes Vermeer and Frans van Mieris

S9 J Shields Lecture

01:40 p.m. - 01:45 p.m.

Introduction

Presenter: Jesse Berry (United States)

01:45 p.m. - 02:00 p.m.

J Shields Lecture

Presenter: Carol L. Shields (United States)

02:00 p.m. - 03:30 p.m.

Johannes Vermeer and Frans van Mieris

S10 Retinoblastoma: Basic Science and Cases

Moderators: Jesse Berry (United States), Josephine Dorsman (The Netherlands), Theodora Hadjistilianou (Italy) & Matthew Wilson (United States)

02:00 p.m. - 02:08 p.m.

Proteomics of aqueous humor as a source of disease biomarkers in retinoblastoma

Presenter: Angela Galardi (Italy)

02:08 p.m. - 02:16 p.m.

What can the aqueous humor liquid biopsy do? Establishing clinical utility of ctDNA analysis for diagnosis, prognosis, and treatment monitoring of retinoblastoma

Presenter: Jesse Berry (United States)

02:16 p.m. - 02:24 p.m.

Identifying DNA methylation signatures of retinoblastoma via aqueous humor, an ocular liquid biopsy

Presenter: Liya Xu (United States)

02:24 p.m. - 02:32 p.m.

Retinoblastoma from human stem cell-derived retinal organoids

Presenter: Matthew Wilson (United States)

02:32 p.m. - 02:40 p.m.

Phase I sustained-release topotecan episcleral plaque (chemoplaque) for retinoblastoma (STEP-RB)

Presenter: Brenda Gallie (Canada)

02:40 p.m. - 02:48 p.m.

Subretinal grafts of patient-derived retinoblastoma cells in rats reflect different clinical patterns

Presenter: Denis Malaise (France)

02:48 p.m. - 02:56 p.m.

Can pre-enucleation plasma cfDNA predict which retinoblastoma patients with choroidal invasion will develop metastases?

Presenter: Jasmine Francis (United States)

02:56 p.m. - 03:04 p.m.

Investigating the aqueous humor and tumor tissue of naïve retinoblastoma eyes in a next‐generation sequencing panel for pediatric malignancies

Presenter: Indhira Oliveira (Brazil)

03:04 p.m. - 03:06 p.m.

Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Presenter: Jesse Berry (United States)

03:06 p.m. - 03:08 p.m.

Disruption of RB1 exon 5 donor splice site leading to reduced penetrance parent-of-origin effect in two unrelated families

Presenter: Hilary Racher (Canada)

03:08 p.m. - 03:10 p.m.

Single injection of intracameral chemotherapy for chemo-resistant retinoblastoma with aqueous seeding

Presenter: Swathi Kaliki (India)

03:10 p.m. - 03:12 p.m.

Unique case of discordant phenotype-genotype analysis in RB: Additional factors at play?

Presenter: Katherine Paton (Canada)

02:00 p.m. - 03:30 p.m.

Godfried Schalcken

Poster session Uveal Melanoma 2.1 - cont.

Moderators: Maura Di Nicola (United States), Nanda Horeweg (The Netherlands) & Hatem Krema (Canada)

Post-operative echography for optimization of radiation dosimetry in patients with posterior uveal melanoma treated with plaque brachytherapy

Presenter: Elaine Binkley (United States)

Gene expression profile and local tumor recurrence of irradiated uveal melanomas

Presenter: Maura Di Nicola (United States)

Oncological outcome and eye preservation in the first year of a new proton therapy center

Presenter: Nanda Horeweg (The Netherlands)

Impact of local availability of proton therapy for uveal melanoma on visual outcome

Presenter: Nanda Horeweg (The Netherlands)

41-gauge fine-needle aspiration biopsy for intraocular tumor

Presenter: Min Kim (South Korea)

Laser treatment for choroidal melanoma

Presenter: Abhilasha Maheshwari (United States)

Iris melanoma and sudden death

Presenter: Scott Oliver (United States)

Clinical utility of preoperative dosimetry for brachytherapy in uveal melanoma

Presenter: Scott Oliver (United States)

Telomerase gene promoter (TERT) mutation in recurrent uveal melanoma after secondary enucleation revealed by targeted next-generation sequencing

Presenter: Brittany Perzia (United States)

Can the late effects of fractionated stereotactic radiotherapy for posterior choroidal melanoma be reduced and allow useful vision preservation without compromising metastasis-free survival? A pilot study

Presenter: Claire Phillips (Australia)

Comparison of MRI-based and conventional measurements for proton beam therapy of uveal melanoma

Presenter: Berit Verbist (The Netherlands)

Asymmetric loading of Iodine-125 episcleral plaques: Indications and outcomes

Presenter: Filiberto Altomare (Canada)

Epiphora following specialised teletherapy to medially located ocular tumours

Presenter: Umiya Harley (United Kingdom)

Accuracy of residual interfraction patient positioning in Ocular Proton Therapy (OPT)

Presenter: Martijn Hol (The Netherlands)

Inter-observer variability in MR-based target volume delineation of uveal melanoma

Presenter: Lisa Klaassen (The Netherlands)

3D MRI tumour measurements compared to conventional ultrasound for treatment planning of eye tumours

Presenter: Lisa Klaassen (The Netherlands)

Biopsies of intraocular tumors - A retrospective analysis from 2017 to 2019

Presenter: Stefan H. Kreis (Germany)

Germline genetic testing for uveal melanoma: A simplified process

Presenter: Hatem Krema (Canada)

Demographic and clinical characterization of uveal melanoma patients in a German ophthalmic oncology reference center between 2007 and 2021

Presenter: Mael Lever (Germany)

02:00 p.m. - 03:30 p.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 2.2 - cont.

Moderators: Jan-Willem Beenakker (The Netherlands), Hung-Da Chou (Taiwan) & Vicktoria (vicky) Vishnevskia-Dai (Israel)

Amelanotic melanoma presenting as tubercular granuloma

Presenter: Vishal Raval (India)

Small choroidal melanoma presenting with submacular hemorrhage

Presenter: Pukhraj Rishi (United States)

MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma

Presenter: Michael Tang (The Netherlands)

Spontaneous metastasis of uveal melanoma in a mouse orthotopic xenograft model

Presenter: Raquel Ramos (Spain)

Clinical indications for an MRI for uveal melanoma patients

Presenter: Jan-Willem Beenakker (The Netherlands)

Using proton beam therapy without preplaced fiducial markers for choroidal melanoma: A preliminary report from a single institute in Asia

Presenter: Hung-Da Chou (Taiwan)

How do Australian optometrists and ophthalmologists manage choroidal naevi?

Presenter: Michele C. Madigan (Australia)

I-125 plaque radiation compared with proton radiation for treatment of uveal melanoma

Presenter: Arman Mashayekhi (United States)

Uveal melanoma surgical approach trough endoresection: A monocentric experience

Presenter: Cinzia Mazzini (Italy)

Long-term visual outcomes of patients with temporal uveal melanoma treated with proton beam radiotherapy

Presenter: Sacha Nahon-Esteve (France)

Is ultrasonographic hollowness a prognostic biomarker to identify amelanotic choroidal nevi at risk of transformation into melanoma?

Presenter: Monica Maria Pagliara (Italy)

Endoresection as primary or secondary management of choroidal melanoma

Presenter: David Reichstein (United States)

Conditional survival of uveal melanoma using The Cancer Genome Atlas (TCGA) classification (Simplified Version) in 1001 Cases

Presenter: Carol L. Shields (United States)

Radiation retinopathy: Pilot use of long-acting intravitreal fluocinolone implant

Presenter: Janani Singaravelu (United States)

Long term clinical outcomes with dedicated proton ocular beam and helium ion radiation for uveal melanoma patients aged 45 and younger

Presenter: Carly Zako (United States)

Uveal melanoma patients reported outcomes (PROMS)

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

Uveal melanoma patient attitudes towards prognostic testing using gene expression profiling

Presenter: Basil Williams (United States)

Consensus statement for metastatic surveillance of uveal melanomas in Scotland

Presenter: Vikas Chadha (United Kingdom)

03:30 p.m. - 04:00 p.m.

Coffee break

03:30 p.m. - 04:00 p.m.

Godfried Schalcken

Poster session Retinoblastoma 2.1 - cont.

Moderators: Helen Dimaras (Canada) & Ido Didi Fabian (Israel)

Identification of novel genes by targeted exome sequencing in retinoblastoma

Presenter: Bhavna Chawla (India)

Ab interno non filtrating glaucoma surgery for the treatment of angle-closure glaucoma in retinoblastoma

Presenter: Christina Stathopoulos (Switzerland)

Myelosuppression after intra-arterial chemotherapy for intraocular retinoblastoma with or without prior systemic chemotherapy

Presenter: Concetta Didomenico (United States)

Impact of choroidal invasion on survival from retinoblastoma using a US national database

Presenter: Dan S. Gombos (United States)

Clearance of tumor-derived extracellular vesicle heterogeneity in aqueous humor after chemotherapy in retinoblastoma eyes

Presenter: Deborah Im (United States)

Outcome of silicone vs PMMA orbital implants following minimal manipulation myoconjunctival enucleation in retinoblastoma

Presenter: Harika Regani (India)

Patient reported outcome measures for retinoblastoma

Presenter: Helen Dimaras (Canada)

Retinoblastoma tumor DNA testing can decrease residual germline risk in unilateral patients

Presenter: Hilary Racher (Canada)

When RB met RP

Presenter: Ido Didi Fabian (Israel)

03:30 p.m. - 04:00 p.m.

Pieter van Slingelandt

Poster session Retinoblastoma 2.2 - cont.

Moderators: Nathalie Cassoux (France), Vishal Raval (India) & Mrittika Sen (United States)

Safety-enhanced cataract surgery in children with retinoblastoma: A retrospective case series

Presenter: Mrittika Sen (United States)

Emerging disease: Spiroplasma - Related uveitis in newborns masquerading anterior retinoblastoma

Presenter: Nathalie Cassoux (France)

Impact of the Covid-19 pandemic on the care and follow up of retinoblastoma patients in Senegal

Presenter: Paule Aïda Roth (Senegal)

Biochemical measures of ovarian function in female survivors of retinoblastoma treated with intra-arterial melphalan: An initial report

Presenter: Priya Marathe (United States)

Influence of SARS-CoV-2 pandemic on retinoblastoma presentation – data from an European national reference center

Presenter: Tobias Kiefer (Germany)

Analysis of referral pattern and pathways of retinoblastoma cases in Ghana

Presenter: Helen Dimaras (Canada)

Epidemiological and clinical profile of retinoblastoma in Ghana: A baseline national survey

Presenter: Helen Dimaras (Canada)

Proteome analysis of WERI RB1 and etoposide resistant WERI ETOR retinoblastoma cell lines

Presenter: Vinodh Kakkassery (Germany)

Macular retinoblastoma: Clinical presentation and treatment outcomes

Presenter: Vishal Raval (India)

Impact of adjuvant therapy on outcome of massive choroidal invasion of retinoblastoma

Presenter: Zhao Xun Feng (Canada)

04:00 p.m. - 05:00 p.m.

Johannes Vermeer and Frans van Mieris

S11 Retinoblastoma: International Studies

Moderators: Laurence Desjardins (France), Ido Didi Fabian (Israel), Maria Manquez Hatta (Chile) & Prithvi Mruthyunjaya (United States)

04:00 p.m. - 04:08 p.m.

Global retinoblastoma outcome study: Analysis of 4,064 patients from 149 countries

Presenter: Ido Didi Fabian (Israel)

04:08 p.m. - 04:16 p.m.

Artificial intelligence and machine learning in ocular oncology: Retinoblastoma

Presenter: Swathi Kaliki (India)

04:16 p.m. - 04:24 p.m.

How telemedicine and centralized care changed the natural history of retinoblastoma in a developing country: Analysis of 478 patients treated over 17 years

Presenter: Yacoub Yousef (Jordan)

04:24 p.m. - 04:32 p.m.

Advanced unilateral retinoblastoma requiring enucleation: European standard clinical practice guidelines

Presenter: Alexandre Matet (France)

04:32 p.m. - 04:40 p.m.

A global online retinoblastoma academy

Presenter: Matthew Wilson (United States)

04:40 p.m. - 04:48 p.m.

Leukocoria detector app - Highs & lows on implementation in a developing country

Presenter: Maria Manquez Hatta (Chile)

04:48 p.m. - 04:56 p.m.

Programme to improve retinoblastoma care in subsaharan Africa

Presenter: Laurence Desjardins (France)

05:00 p.m. - 07:00 p.m.

Boat tour through the Leiden canals

07:00 p.m. - 08:00 p.m.

Industry Reception

Sunday, June 19, 2022

08:00 a.m. - 08:45 a.m.

Johannes Vermeer and Frans van Mieris

I3 - Industry Presentation Eckert & Ziegler BEBIG - An update on Ru-106 brachytherapy and related topics

08:02 a.m. - 08:14 a.m.

Ruthenium brachytherapy or Proton beam: How to make a sound decision

Presenter: Marina Marinkovic (The Netherlands)

08:14 a.m. - 08:26 a.m.

How MRI can help optimize the treatment of uveal melanoma

Presenter: Jan-Willem Beenakker (The Netherlands)

08:26 a.m. - 08:38 a.m.

How I place a Ru-106 plaque just where I want it to be

Presenter: Bertil Damato (United Kingdom/Sweden)

08:38 a.m. - 08:45 a.m.

Technical Details on Ru-106 Eye Applicators

Presenter: Carmen Schulz (Germany)

08:00 a.m. - 09:00 a.m.

Singel walk

08:00 a.m. - 09:00 a.m.

Godfried Schalcken

Poster session Uveal Melanoma 2.1

Moderators: Maura Di Nicola (United States), Nanda Horeweg (The Netherlands) & Hatem Krema (Canada)

Post-operative echography for optimization of radiation dosimetry in patients with posterior uveal melanoma treated with plaque brachytherapy

Presenter: Elaine Binkley (United States)

Gene expression profile and local tumor recurrence of irradiated uveal melanomas

Presenter: Maura Di Nicola (United States)

Oncological outcome and eye preservation in the first year of a new proton therapy center

Presenter: Nanda Horeweg (The Netherlands)

Impact of local availability of proton therapy for uveal melanoma on visual outcome

Presenter: Nanda Horeweg (The Netherlands)

41-gauge fine-needle aspiration biopsy for intraocular tumor

Presenter: Min Kim (South Korea)

Laser treatment for choroidal melanoma

Presenter: Abhilasha Maheshwari (United States)

Iris melanoma and sudden death

Presenter: Scott Oliver (United States)

Clinical utility of preoperative dosimetry for brachytherapy in uveal melanoma

Presenter: Scott Oliver (United States)

Telomerase gene promoter (TERT) mutation in recurrent uveal melanoma after secondary enucleation revealed by targeted next-generation sequencing

Presenter: Brittany Perzia (United States)

Presenter: Claire Phillips (Australia)

Comparison of MRI-based and conventional measurements for proton beam therapy of uveal melanoma

Presenter: Berit Verbist (The Netherlands)

Asymmetric loading of Iodine-125 episcleral plaques: Indications and outcomes

Presenter: Filiberto Altomare (Canada)

Epiphora following specialised teletherapy to medially located ocular tumours

Presenter: Umiya Harley (United Kingdom)

Accuracy of residual interfraction patient positioning in Ocular Proton Therapy (OPT)

Presenter: Martijn Hol (The Netherlands)

Inter-observer variability in MR-based target volume delineation of uveal melanoma

Presenter: Lisa Klaassen (The Netherlands)

3D MRI tumour measurements compared to conventional ultrasound for treatment planning of eye tumours

Presenter: Lisa Klaassen (The Netherlands)

Biopsies of intraocular tumors - A retrospective analysis from 2017 to 2019

Presenter: Stefan H. Kreis (Germany)

Germline genetic testing for uveal melanoma: A simplified process

Presenter: Hatem Krema (Canada)

Demographic and clinical characterization of uveal melanoma patients in a German ophthalmic oncology reference center between 2007 and 2021

Presenter: Mael Lever (Germany)

08:00 a.m. - 09:00 a.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 2.2

Moderators: Jan-Willem Beenakker (The Netherlands), Hung-Da Chou (Taiwan) & Michael Tang (The Netherlands)

Amelanotic melanoma presenting as tubercular granuloma

Presenter: Vishal Raval (India)

Small choroidal melanoma presenting with submacular hemorrhage

Presenter: Pukhraj Rishi (United States)

MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma

Presenter: Michael Tang (The Netherlands)

Spontaneous metastasis of uveal melanoma in a mouse orthotopic xenograft model

Presenter: Raquel Ramos (Spain)

Clinical indications for an MRI for uveal melanoma patients

Presenter: Jan-Willem Beenakker (The Netherlands)

Using proton beam therapy without preplaced fiducial markers for choroidal melanoma: A preliminary report from a single institute in Asia

Presenter: Hung-Da Chou (Taiwan)

How do Australian optometrists and ophthalmologists manage choroidal naevi?

Presenter: Michele C. Madigan (Australia)

I-125 plaque radiation compared with proton radiation for treatment of uveal melanoma

Presenter: Arman Mashayekhi (United States)

Uveal melanoma surgical approach trough endoresection: A monocentric experience

Presenter: Cinzia Mazzini (Italy)

Long-term visual outcomes of patients with temporal uveal melanoma treated with proton beam radiotherapy

Presenter: Sacha Nahon-Esteve (France)

Is ultrasonographic hollowness a prognostic biomarker to identify amelanotic choroidal nevi at risk of transformation into melanoma?

Presenter: Monica Maria Pagliara (Italy)

Endoresection as primary or secondary management of choroidal melanoma

Presenter: David Reichstein (United States)

Conditional survival of uveal melanoma using The Cancer Genome Atlas (TCGA) classification (Simplified Version) in 1001 Cases

Presenter: Carol L. Shields (United States)

Radiation retinopathy: Pilot use of long-acting intravitreal fluocinolone implant

Presenter: Janani Singaravelu (United States)

Long term clinical outcomes with dedicated proton ocular beam and helium ion radiation for uveal melanoma patients aged 45 and younger

Presenter: Carly Zako (United States)

Uveal melanoma patients reported outcomes (PROMS)

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

Uveal melanoma patient attitudes towards prognostic testing using gene expression profiling

Presenter: Basil Williams (United States)

Consensus statement for metastatic surveillance of uveal melanomas in Scotland

Presenter: Vikas Chadha (United Kingdom)

09:00 a.m. - 10:30 a.m.

Johannes Vermeer and Frans van Mieris

S12 - Uveal melanoma, basic

Moderators: Zelia Correa (United States), Emine Kiliç (The Netherlands), Edoardo Midena (Italy) & Alexandre Moulin (Switzerland)

09:00 a.m. - 09:07 a.m.

Trends in epidemiology of ocular melanoma

Presenter: Emine Kiliç (The Netherlands)

09:07 a.m. - 09:14 a.m.

Germline MBD4 Mutations and predisposition to uveal melanoma

Presenter: Anais Le Ven (France)

09:14 a.m. - 09:21 a.m.

Exploiting a human eye organoid model to understand the role of BAP1 in uveal melanoma metastasis

Presenter: Priya Begani (United States)

09:21 a.m. - 09:28 a.m.

Cell-free tumor DNA as a target for biomarker analysis in patients with uveal melanoma (UM): Suitability for prognostic testing

Presenter: Claudia H.d. Le Guin (Germany)

09:28 a.m. - 09:35 a.m.

In vivo liquid biopsy of uveal melanoma: An aqueous humor proteomic study

Presenter: Edoardo Midena (Italy)

09:35 a.m. - 09:42 a.m.

Electrochemotherapy as a therapeutic radiosentitizing modality in 3D spheroids of primary uveal melanoma cell lines

Presenter: Miltiadis Fiorentzis (Germany)

09:42 a.m. - 09:49 a.m.

A phase 1 study of percutaneous autolytic rose bengal disodium for metastatic uveal melanoma patients with hepatic metastases

Presenter: Krysta Mcvay (United States)

09:49 a.m. - 09:56 a.m.

Prognostic significance of tumor infiltrating lymphocytes and immune checkpoint markers in uveal melanoma

Presenter: Lata Singh (India)

09:56 a.m. - 10:03 a.m.

Direct gene expression profile prediction for uveal melanoma from digital cytopathology images via deep learning and salient image region identification

Presenter: Zelia Correa (United States)

10:03 a.m. - 10:10 a.m.

CyberKnife vs protons: What might be the best approach to reduce complications in posterior uveal melanomas?

Presenter: Emma Fleury (The Netherlands)

10:10 a.m. - 10:17 a.m.

Pilot clinical study of ocular prosthesis manufacture using three-dimensional (3D) printing

Presenter: Mandeep Sagoo (United Kingdom)

10:17 a.m. - 10:24 a.m.

Medium to long-term results of Baerveldt shunt surgery for glaucoma secondary to anterior uveal melanoma treated with proton therapy

Presenter: Ann Schalenbourg (Switzerland)

10:30 a.m. - 11:00 a.m.

Coffee break

10:30 a.m. - 11:00 a.m.

Godfried Schalcken

Poster session Uveal Melanoma 2.1 - cont.

Moderators: Maura Di Nicola (United States), Nanda Horeweg (The Netherlands) & Hatem Krema (Canada)

Post-operative echography for optimization of radiation dosimetry in patients with posterior uveal melanoma treated with plaque brachytherapy

Presenter: Elaine Binkley (United States)

Gene expression profile and local tumor recurrence of irradiated uveal melanomas

Presenter: Maura Di Nicola (United States)

Oncological outcome and eye preservation in the first year of a new proton therapy center

Presenter: Nanda Horeweg (The Netherlands)

Impact of local availability of proton therapy for uveal melanoma on visual outcome

Presenter: Nanda Horeweg (The Netherlands)

41-gauge fine-needle aspiration biopsy for intraocular tumor

Presenter: Min Kim (South Korea)

Laser treatment for choroidal melanoma

Presenter: Abhilasha Maheshwari (United States)

Iris melanoma and sudden death

Presenter: Scott Oliver (United States)

Clinical utility of preoperative dosimetry for brachytherapy in uveal melanoma

Presenter: Scott Oliver (United States)

Telomerase gene promoter (TERT) mutation in recurrent uveal melanoma after secondary enucleation revealed by targeted next-generation sequencing

Presenter: Brittany Perzia (United States)

Presenter: Claire Phillips (Australia)

Comparison of MRI-based and conventional measurements for proton beam therapy of uveal melanoma

Presenter: Berit Verbist (The Netherlands)

Asymmetric loading of Iodine-125 episcleral plaques: Indications and outcomes

Presenter: Filiberto Altomare (Canada)

Epiphora following specialised teletherapy to medially located ocular tumours

Presenter: Umiya Harley (United Kingdom)

Accuracy of residual interfraction patient positioning in Ocular Proton Therapy (OPT)

Presenter: Martijn Hol (The Netherlands)

Inter-observer variability in MR-based target volume delineation of uveal melanoma

Presenter: Lisa Klaassen (The Netherlands)

3D MRI tumour measurements compared to conventional ultrasound for treatment planning of eye tumours

Presenter: Lisa Klaassen (The Netherlands)

Biopsies of intraocular tumors - A retrospective analysis from 2017 to 2019

Presenter: Stefan H. Kreis (Germany)

Germline genetic testing for uveal melanoma: A simplified process

Presenter: Hatem Krema (Canada)

Demographic and clinical characterization of uveal melanoma patients in a German ophthalmic oncology reference center between 2007 and 2021

Presenter: Mael Lever (Germany)

10:30 a.m. - 11:00 a.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 2.2 - cont.

Moderators: Jan-Willem Beenakker (The Netherlands), Hung-Da Chou (Taiwan) & Michael Tang (The Netherlands)

Amelanotic melanoma presenting as tubercular granuloma

Presenter: Vishal Raval (India)

Small choroidal melanoma presenting with submacular hemorrhage

Presenter: Pukhraj Rishi (United States)

MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma

Presenter: Michael Tang (The Netherlands)

Spontaneous metastasis of uveal melanoma in a mouse orthotopic xenograft model

Presenter: Raquel Ramos (Spain)

Clinical indications for an MRI for uveal melanoma patients

Presenter: Jan-Willem Beenakker (The Netherlands)

Using proton beam therapy without preplaced fiducial markers for choroidal melanoma: A preliminary report from a single institute in Asia

Presenter: Hung-Da Chou (Taiwan)

How do Australian optometrists and ophthalmologists manage choroidal naevi?

Presenter: Michele C. Madigan (Australia)

I-125 plaque radiation compared with proton radiation for treatment of uveal melanoma

Presenter: Arman Mashayekhi (United States)

Uveal melanoma surgical approach trough endoresection: A monocentric experience

Presenter: Cinzia Mazzini (Italy)

Long-term visual outcomes of patients with temporal uveal melanoma treated with proton beam radiotherapy

Presenter: Sacha Nahon-Esteve (France)

Is ultrasonographic hollowness a prognostic biomarker to identify amelanotic choroidal nevi at risk of transformation into melanoma?

Presenter: Monica Maria Pagliara (Italy)

Endoresection as primary or secondary management of choroidal melanoma

Presenter: David Reichstein (United States)

Conditional survival of uveal melanoma using The Cancer Genome Atlas (TCGA) classification (Simplified Version) in 1001 Cases

Presenter: Carol L. Shields (United States)

Radiation retinopathy: Pilot use of long-acting intravitreal fluocinolone implant

Presenter: Janani Singaravelu (United States)

Long term clinical outcomes with dedicated proton ocular beam and helium ion radiation for uveal melanoma patients aged 45 and younger

Presenter: Carly Zako (United States)

Uveal melanoma patients reported outcomes (PROMS)

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

Uveal melanoma patient attitudes towards prognostic testing using gene expression profiling

Presenter: Basil Williams (United States)

Consensus statement for metastatic surveillance of uveal melanomas in Scotland

Presenter: Vikas Chadha (United Kingdom)

11:00 a.m. - 12:30 p.m.

Johannes Vermeer and Frans van Mieris

S13 Uveal Melanoma: Clinic and Cases

Moderators: Lauren Dalvin (United States), Marina Marinkovic (The Netherlands), Mandeep Sagoo (United Kingdom) & Ann Schalenbourg (Switzerland)

11:00 a.m. - 11:08 a.m.

MR imaging characteristics of uveal melanoma with histopathological validation

Presenter: Teresa Ferreira (The Netherlands)

11:08 a.m. - 11:16 a.m.

Ultrasound guidance of plaque placement for choroidal melanoma

Presenter: Brian Marr (United States)

11:16 a.m. - 11:24 a.m.

Prognostic biopsies in small choroidal melanomas

Presenter: Rumana Hussain (United Kingdom)

11:24 a.m. - 11:32 a.m.

A phase 2 trial of a first in class targeted therapy for choroidal melanoma via suprachoroidal (SC) administration

Presenter: Ivana Kim (United States)

11:32 a.m. - 11:40 a.m.

Transscleral resection in large uveal melanoma

Presenter: Nikos Bechrakis (Germany)

11:40 a.m. - 11:48 a.m.

Survival after proton therapy for patients with recurrent uveal melanoma

Presenter: Evangelos Gragoudas (United States)

11:48 a.m. - 11:51 a.m.

Association of plasma circulating tumor DNA with diagnosis of metastatic uveal melanoma

Presenter: Jasmine Francis (United States)

11:51 a.m. - 11:54 a.m.

Bilateral nevus of Ota

Presenter: Ana Marisa Castello Branco (Brazil)

11:54 a.m. - 11:57 a.m.

Necrotic eruption of an untreated, inflammatory choroidal melanoma

Presenter: Andrew Stacey (United States)

11:57 a.m. - 12:00 p.m.

A slithery coincidence?

Presenter: Prithvi Mruthyunjaya (United States)

12:00 p.m. - 12:03 p.m.

Uveal melanoma extrascleral orbital invasions - Report of three cases in 19 years

Presenter: Vincenzina Mazzeo (Italy)

12:03 p.m. - 12:06 p.m.

Chronic exudative retinal detachment with underlying choroidal mass

Presenter: Lauren Dalvin (United States)

12:06 p.m. - 12:09 p.m.

To see or not to see, that is the question

Presenter: Sara Lally (United States)

12:09 p.m. - 12:12 p.m.

Clinical phenotype of patient with germline MBD4 pathogenic alteration: Monosomy 3 uveal melanoma with long survival

Presenter: Colleen M. Cebulla (United States)

12:12 p.m. - 12:20 p.m.

Vitreous proteomics by mass spectrometry correlates with gene expression profile of uveal melanoma

Presenter: Prithvi Mruthyunjaya (United States)

12:30 p.m. - 01:15 p.m.

Johannes Vermeer and Frans van Mieris

Industry Presentation AURA - New Developments in AU-011, an Investigational Virus-Like Drug Conjugate (VDC) for treatment of Ocular Cancer and Metastatic Disease

12:30 p.m. - 12:35 p.m.

Introduction

Presenter: Elisabet de Los Pinos (United States)

12:36 p.m. - 12:45 p.m.

AU-011 Overview and Update on Choroidal Metastasis

Presenter: Cadmus Rich (United States)

12:46 p.m. - 12:55 p.m.

Clinical Development of AU-011

Presenter: Abhijit Narvekar (United States)

12:56 p.m. - 01:05 p.m.

AU-011 in combination with immune checkpoint inhibitors for the treatment of primary tumors and distant metastasis

Presenter: Ruben Huis In 't Veld (The Netherlands)

01:06 p.m. - 01:15 p.m.

Discussion

Presenter: Cadmus Rich (United States)

12:30 p.m. - 01:40 p.m.

Lunch

12:30 p.m. - 01:40 p.m.

Jan Steen

Poster session Uveal Melanoma 3.1

Moderators: Maria Chiara Gelmi (The Netherlands), Rosaria Gangemi (Italy) & Dan S. Gombos (United States)

Metastatic risk factors associated with Class 1A uveal melanoma patients

Presenter: Alexej Ballhausen (United States)

Choroidal melanoma tumor profile and treatment pattern for newly diagnosed patients in Brazil

Presenter: Arthur Fernandes (Brazil)

New molecular target therapies for uveal melanoma

Presenter: Rosaria Gangemi (Italy)

Plaque brachytherapy for the treatment of uveal melanoma: Our strategies and results - The experience of University of Pisa

Presenter: Federica Genovesi Ebert (Italy)

Stereotactic radiosurgery, a really promise in the management of selected uveal melanoma

Presenter: Federica Genovesi Ebert (Italy)

Prediction of metastatic risk using GEP, PRAME, COMS, and AJCC uveal melanoma

Presenter: Scott Oliver (United States)

12:30 p.m. - 01:40 p.m.

Godfried Schalcken

Poster session Uveal Melanoma 3.2

Moderators: Colleen M. Cebulla (United States), Maya Eiger-Moscovich (Israel) & Vincent Sun (Canada)

In vitro results of a novel virus like drug conjugate targeted therapy in uveal melanoma suggest immunostimulatory capacity

Presenter: Ma Sen (The Netherlands)

Very long-term outcomes of Anti-VEGF therapy for radiation maculopathy after ophthalmic brachytherapy

Presenter: Puneet Jain (India)

BAP1 immunohistochemistry in post-brachytherapy uveal melanoma

Presenter: Maya Eiger-Moscovich (Israel)

A novel approach to estimating choroidal lesion thickness using 2D ultra-widefield optomap images

Presenter: Michael Yu (United States)

De novo choroidal melanoma

Presenter: Emily Zabor (United States)

Chandelier-assisted brachytherapy for uveal melanoma

Presenter: Colleen M. Cebulla (United States)

Proton beam therapy for uveal melanomas - When do we see a response?

Presenter: Matthew Gillam (United Kingdom)

12:30 p.m. - 01:40 p.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 3.3

Moderators: Niels Brouwer (The Netherlands), Michael Heiferman (United States) & Aqsa Saleem (Canada)

Loss of cilia in uveal melanoma: Implications for diagnosis

Presenter: Michael Heiferman (United States)

Preliminary results of uveal melanoma treated with iodine-125 plaques: Analysis of disease control and visual outcomes with 63 Gy to the target volume

Presenter: Wajiha Kheir (Lebanon)

Evaluation of radiation maculopathy after treatment of choroidal melanoma with ruthenium-106 using optical coherence tomography angiography

Presenter: Hamid Riazi Esfahani (Iran)

Strabismus post plaque brachytherapy

Presenter: Aqsa Saleem (Canada)

BAP1 immunostain status in intraocular biopsy specimens for uveal melanoma correlates with other prognostic markers

Presenter: Diva Salomao (United States)

Uveal melanoma inpatient with oculo-dermal nevus of Ota (clinical case)

Presenter: Alua Aubakirova (Kazakhstan)

01:40 p.m. - 02:00 p.m.

Johannes Vermeer and Frans van Mieris

S14 Stallard Lecture

01:40 p.m. - 01:45 p.m.

Introduction to Prof Kivela, Stallard lecturer

Presenter: Dan S. Gombos (United States)

01:45 p.m. - 02:00 p.m.

Stallard Lecture

Presenter: Tero T. Kivelä (Finland)

02:00 p.m. - 03:30 p.m.

Johannes Vermeer and Frans van Mieris

S15 Uveal Melanoma - Basic and Clinical approaches to Uveal Melanoma Metastases

Moderators: Richard Carvajal (United States), Sapna Patel (United States), Alison Skalet (United States) & Serdar Yavuzyigitoglu (The Netherlands)

02:00 p.m. - 02:08 p.m.

The role of MET inhibition on the efficacy of CDK4/6 inhibitors in metastatic uveal melanoma

Presenter: Mizue Terai (United States)

02:08 p.m. - 02:16 p.m.

A novel virus like drug conjugate in combination with immune checkpoint inhibitors for the treatment of primary choroidal tumors and distant metastasis

Presenter: Ruben Huis In 't Veld (The Netherlands)

02:16 p.m. - 02:24 p.m.

Chimeric antigens in immunotargeting of G-alpha mutated uveal melanoma

Presenter: Vitali Alexeev (United States)

02:24 p.m. - 02:32 p.m.

Uveal melanoma-derived exosomes contribute to promote the pre-metastatic niche in the liver by reprograming the hepatic stellate cells

Presenter: Raquel Ramos (Spain)

02:32 p.m. - 02:40 p.m.

Development and utilization of hepatic metastasis mouse models in uveal melanoma

Presenter: Takami Sato (United States)

02:40 p.m. - 02:48 p.m.

Circulating hybrid cells as a novel prognostic biomarker in uveal melanoma

Presenter: Alison Skalet (United States)

02:48 p.m. - 02:56 p.m.

Testing ruthenium-based photoactivated chemotherapy on tumor-bearing mice models as a new treatment for uveal melanoma

Presenter: Ludovic Bretin (The Netherlands)

02:56 p.m. - 03:04 p.m.

Clinical and tumor characteristics of patients with metastatic uveal melanoma (mUM) who develop brain metastases (BM)

Presenter: Alexander Z. Wei (United States)

03:04 p.m. - 03:12 p.m.

Hepatic miliary metastases in patients with uveal melanoma

Presenter: Serdar Yavuzyigitoglu (The Netherlands)

03:12 p.m. - 03:20 p.m.

Intermittent MEK inhibition for the treatment of Metastatic Uveal Melanoma (MUM)

Presenter: Richard Carvajal (United States)

03:20 p.m. - 03:23 p.m.

Metabolic complete responses (mCR) in metastatic uveal melanoma (mUM) patients treated with image-guided injection (IGI) of PV-10

Presenter: Sapna Patel (United States)

03:23 p.m. - 03:31 p.m.

Optical density ratio of subretinal fluid in choroidal melanoma versus choroidal naevus

Presenter: Alexandre Matet (France)

03:30 p.m. - 04:00 p.m.

Coffee break

03:30 p.m. - 04:00 p.m.

Jan Steen

Poster session Uveal Melanoma 3.1 - cont.

Moderators: Maria Chiara Gelmi (The Netherlands), Rosaria Gangemi (Italy) & Dan S. Gombos (United States)

Metastatic risk factors associated with Class 1A uveal melanoma patients

Presenter: Alexej Ballhausen (United States)

Choroidal melanoma tumor profile and treatment pattern for newly diagnosed patients in Brazil

Presenter: Arthur Fernandes (Brazil)

New molecular target therapies for uveal melanoma

Presenter: Rosaria Gangemi (Italy)

Plaque brachytherapy for the treatment of uveal melanoma: Our strategies and results - The experience of University of Pisa

Presenter: Federica Genovesi Ebert (Italy)

Stereotactic radiosurgery, a really promise in the management of selected uveal melanoma

Presenter: Federica Genovesi Ebert (Italy)

Prediction of metastatic risk using GEP, PRAME, COMS, and AJCC uveal melanoma

Presenter: Scott Oliver (United States)

03:30 p.m. - 04:00 p.m.

Godfried Schalcken

Poster session Uveal Melanoma 3.2 - cont.

Moderators: Colleen M. Cebulla (United States), Maya Eiger-Moscovich (Israel) & Vincent Sun (Canada)

In vitro results of a novel virus like drug conjugate targeted therapy in uveal melanoma suggest immunostimulatory capacity

Presenter: Ma Sen (The Netherlands)

Very long-term outcomes of Anti-VEGF therapy for radiation maculopathy after ophthalmic brachytherapy

Presenter: Puneet Jain (India)

BAP1 immunohistochemistry in post-brachytherapy uveal melanoma

Presenter: Maya Eiger-Moscovich (Israel)

A novel approach to estimating choroidal lesion thickness using 2D ultra-widefield optomap images

Presenter: Michael Yu (United States)

De novo choroidal melanoma

Presenter: Emily Zabor (United States)

Chandelier-assisted brachytherapy for uveal melanoma

Presenter: Colleen M. Cebulla (United States)

Proton beam therapy for uveal melanomas - When do we see a response?

Presenter: Matthew Gillam (United Kingdom)

03:30 p.m. - 04:00 p.m.

Pieter van Slingelandt

Poster session Uveal Melanoma 3.3 - cont.

Moderators: Niels Brouwer (The Netherlands), Michael Heiferman (United States) & Aqsa Saleem (Canada)

Loss of cilia in uveal melanoma: Implications for diagnosis

Presenter: Michael Heiferman (United States)

Preliminary results of uveal melanoma treated with iodine-125 plaques: Analysis of disease control and visual outcomes with 63 Gy to the target volume

Presenter: Wajiha Kheir (Lebanon)

Evaluation of radiation maculopathy after treatment of choroidal melanoma with ruthenium-106 using optical coherence tomography angiography

Presenter: Hamid Riazi Esfahani (Iran)

Strabismus post plaque brachytherapy

Presenter: Aqsa Saleem (Canada)

BAP1 immunostain status in intraocular biopsy specimens for uveal melanoma correlates with other prognostic markers

Presenter: Diva Salomao (United States)

Uveal melanoma inpatient with oculo-dermal nevus of Ota (clinical case)

Presenter: Alua Aubakirova (Kazakhstan)

04:00 p.m. - 05:00 p.m.

Johannes Vermeer and Frans van Mieris

S16 ISOO Business Meeting

05:00 p.m. - 07:00 p.m.

Guided Tour through Historial Leiden

07:00 p.m. - 10:00 p.m.

BBQ dinner beach pavilion 'Het Strand'

Monday, June 20, 2022

08:00 a.m. - 08:45 a.m.

Johannes Vermeer and Frans van Mieris

Industry Presentation TriSalus Life Sciences - Enabling Checkpoint Inhibitors in the Liver Through Pressure Enabled Delivery of SD-101

08:00 a.m. - 08:15 a.m.

The science behind the trial design

Presenter: Steven Katz (United States)

08:16 a.m. - 08:30 a.m.

Early trial experience

Presenter: Richard Carvajal (United States)

08:31 a.m. - 08:45 a.m.

Discussion

Presenter: Richard Carvajal (United States)

08:00 a.m. - 09:00 a.m.

Jan Steen

Coffee with Experts - Real-life Tools: Writing and Speaking

08:00 a.m. - 08:15 a.m.

How to apply effectively for a grant

Presenter: Sally Atherton (United States)

08:15 a.m. - 08:30 a.m.

How to create a book

Presenter: Bhavna Chawla (India)

08:30 a.m. - 08:40 a.m.

How to set up effective collaborations

Presenter: Dong Feng Chen (United States)

08:40 a.m. - 08:50 a.m.

Working together in the TCGA

Presenter: Bita Esmaeli (United States)

08:00 a.m. - 09:00 a.m.

Godfried Schalcken

Poster session Other Intraocular Tumours P4.1

Moderators: Zelia Correa (United States), Hakan Demirci (United States) & Annemijn Wierenga (The Netherlands)

Ultra-low-dose (Boom Boom) radiotherapy for cytology-proven primary choroidal lymphoma

Presenter: Kushal Agrawal (United States)

Vitreous metastasis from cutaneous melanoma: Diagnosis and management

Presenter: Zelia Correa (United States)

Treatment of choroidal hemangioma with combined PDT and bevacizumab leads to faster recovery of visual acuity than PDT alone

Presenter: Hakan Demirci (United States)

Unusual patterns in Coats disease

Presenter: Matteo-Maria Girolamo (Italy)

Bilateral sclerochoroidal calcifications: A case report

Presenter: Francesca Guido (Italy)

A case of intraocular malignant teratoid medulloepithelioma of the optic nerve

Presenter: Minglei Han (China)

Vasoactive cavitary lesion in a patient with neurofibromatosis type 1

Presenter: Michael Heiferman (United States)

08:00 a.m. - 09:00 a.m.

Pieter van Slingelandt

Poster session Other Intraocular Tumours P4.2

Moderators: Stephanie Lemaitre (United Kingdom), Vishal Raval (India) & Jill Wells (United States)

Diagnosis of an amelanotic choroidal lesion delayed by a COVID-19 infection

Presenter: Wajiha Kheir (Lebanon)

Ocular metastases from cutaneous melanoma: A report of 3 cases

Presenter: Stephanie Lemaitre (United Kingdom)

Real world outcomes: Reporting clinical results online

Presenter: Abhilasha Maheshwari (United States)

Primary central nervous system lymphoma: Inter-compartmental progression

Presenter: Vishal Raval (India)

Iris tumor: Mystery case

Presenter: Pukhraj Rishi (United States)

Iodine-125 plaque brachytherapy for diffuse choroidal hemangioma: A review of cases

Presenter: Jill Wells (United States)

A rare case of with Histiocytosis (LCH) presented with a histiocytomal amelanotic chorioretinal mass

Presenter: Fariba Ghassemi (Iran)

Educational Course for General Ophthalmologists

08:00 a.m. - 09:00 a.m.

Registration

Educational Course for General Ophthalmologists

09:00 a.m. - 10:00 a.m.

Willem van de Velde

Educational Course for General Ophthalmologists (parallel session)

09:00 a.m. - 10:30 a.m.

Johannes Vermeer and Frans van Mieris

S17 Other Intraocular Tumors

Moderators: Antonia Joussen (Germany), Jens Folke Kiilgaard (Denmark), Timothy Murray (United States) & Katherine Paton (Canada)

09:00 a.m. - 09:08 a.m.

Impact of COVID-19 on features and management of 830 consecutive patients with uveal melanoma

Presenter: Mrittika Sen (United States)

09:08 a.m. - 09:16 a.m.

MOLES – an acronym and scoring system to help non-experts estimate the likelihood of malignancy in melanocytic choroidal tumours

Presenter: Bertil Damato (United Kingdom/Sweden)

09:16 a.m. - 09:24 a.m.

Prognostic impact of methods for measuring tumor size in uveal melanoma

Presenter: Jens Folke Kiilgaard (Denmark)

09:24 a.m. - 09:32 a.m.

The DNA- based genetic testing prognostication versus TNM staging in reference to metastasis and survival of uveal melanoma patients

Presenter: Hatem Krema (Canada)

09:32 a.m. - 09:40 a.m.

A phase 1b/2 trial of AU-011, a first in class targeted therapy for the treatment of choroidal melanoma via intravitreal administration

Presenter: Cadmus Rich (United States)

09:40 a.m. - 09:48 a.m.

Class 2 GEP: Early uveal melanoma treatment for GEP Class 2 tumors reduces mortality

Presenter: Timothy Murray (United States)

09:48 a.m. - 09:56 a.m.

Proton beam for choroidal melanoma – still room for improvement?

Presenter: Antonia Joussen (Germany)

09:56 a.m. - 09:59 a.m.

Cosmetic treatment for scleral pigmentation in a patient with Nevus of Ota

Presenter: Priscilla Ballalai (Brazil)

09:59 a.m. - 10:02 a.m.

Mystery intraocular tumor

Presenter: Ekaterina Semenova (United States)

10:02 a.m. - 10:05 a.m.

Extraocular extension of a uveal melanocytic tumour in a child

Presenter: Mrittika Sen (United States)

10:05 a.m. - 10:08 a.m.

Reactive retinal pigment epithelium hyperplasia in presumed ocular histoplasmosis syndrome

Presenter: Jill Wells (United States)

10:08 a.m. - 10:11 a.m.

MR-imaging of a melanocytoma

Presenter: Teresa Ferreira (The Netherlands)

10:11 a.m. - 10:14 a.m.

Metastatic esophageal carcinoma to the vitreous masquerading as inflammatory vitritis: A case report and literature review

Presenter: Mona Mohammad (Jordan)

10:14 a.m. - 10:17 a.m.

Paraneoplastic cloudy vitelliform submaculopathy could be primary vitreoretinal lymphoma on cytology

Presenter: Kushal Agrawal (United States)

10:17 a.m. - 10:20 a.m.

A case of an unusual retinal mass

Presenter: Elaine Binkley (United States)

10:20 a.m. - 10:23 a.m.

Black swan effect in ophthalmology

Presenter: Gaurav Garg (India)

10:23 a.m. - 10:26 a.m.

Primary choroidal lymphoma presenting as extensive serous retinal detachment and salmon patch of bulbar conjunctiva

Presenter: Hamid Riazi Esfahani (Iran)

10:26 a.m. - 10:29 a.m.

Mystery case

Presenter: Mary Beth Aronow (United States)

10:29 a.m. - 10:32 a.m.

Atypical uveitis in a child

Presenter: Carol L. Shields (United States)

Educational Course for General Ophthalmologists

10:00 a.m. - 10:30 a.m.

Coffee break Educational Course for General Ophthalmologists

10:30 a.m. - 11:00 a.m.

Coffee break

Educational Course for General Ophthalmologists

10:30 a.m. - 11:50 a.m.

Willem van de Velde

Educational Course for General Ophthalmologists (parallel session)

10:30 a.m. - 11:00 a.m.

Godfried Schalcken

Poster session Other Intraocular Tumours P4.1 - cont.

Moderators: Zelia Correa (United States), Hakan Demirci (United States) & Annemijn Wierenga (The Netherlands)

Ultra-low-dose (Boom Boom) radiotherapy for cytology-proven primary choroidal lymphoma

Presenter: Kushal Agrawal (United States)

Vitreous metastasis from cutaneous melanoma: Diagnosis and management

Presenter: Zelia Correa (United States)

Treatment of choroidal hemangioma with combined PDT and bevacizumab leads to faster recovery of visual acuity than PDT alone

Presenter: Hakan Demirci (United States)

Unusual patterns in Coats disease

Presenter: Matteo-Maria Girolamo (Italy)

Bilateral sclerochoroidal calcifications: A case report

Presenter: Francesca Guido (Italy)

A case of intraocular malignant teratoid medulloepithelioma of the optic nerve

Presenter: Minglei Han (China)

Vasoactive cavitary lesion in a patient with neurofibromatosis type 1

Presenter: Michael Heiferman (United States)

10:30 a.m. - 11:00 a.m.

Pieter van Slingelandt

Poster session Other Intraocular Tumours P4.2 - cont.

Moderators: Stephanie Lemaitre (United Kingdom), Vishal Raval (India) & Jill Wells (United States)

Diagnosis of an amelanotic choroidal lesion delayed by a COVID-19 infection

Presenter: Wajiha Kheir (Lebanon)

Ocular metastases from cutaneous melanoma: A report of 3 cases

Presenter: Stephanie Lemaitre (United Kingdom)

Real world outcomes: Reporting clinical results online

Presenter: Abhilasha Maheshwari (United States)

Primary central nervous system lymphoma: Inter-compartmental progression

Presenter: Vishal Raval (India)

Iris tumor: Mystery case

Presenter: Pukhraj Rishi (United States)

Iodine-125 plaque brachytherapy for diffuse choroidal hemangioma: A review of cases

Presenter: Jill Wells (United States)

11:00 a.m. - 12:30 p.m.

Johannes Vermeer and Frans van Mieris

S18 Other intraocular tumors

Moderators: Mary Beth Aronow (United States), Hakan Demirci (United States), Shahar Frenkel (Israel) & Swathi Kaliki (India)

11:00 a.m. - 11:08 a.m.

Surgical tips for the management of combined hamartoma of the retina and retinal pigment epithelium

Presenter: Javier Elizalde (Spain)

11:08 a.m. - 11:16 a.m.

Treatment of aggressive retinal astrocytic hamartoma with oral mTOR inhibition

Presenter: Mary Beth Aronow (United States)

11:16 a.m. - 11:24 a.m.

Vasoproliferative tumours of the retina in long-term observation

Presenter: Iwona Rospond-Kubiak (Poland)

11:24 a.m. - 11:32 a.m.

Grading ocular disease severity in patients with von Hippel-Lindau disease

Presenter: Randy Christopher Bowen (United States)

11:32 a.m. - 11:40 a.m.

BDUMP: New clinical features to aid diagnosis

Presenter: Umiya Harley (United Kingdom)

11:40 a.m. - 11:48 a.m.

CXCR4, CXCR5 and CD44 but not CXCR7 may be involved in homing of primary vitreoretinal lymphoma cells into the eye in a patient derived xenograft mouse model

Presenter: Neele Babst (Germany)

11:48 a.m. - 11:51 a.m.

Atypical reactive lymphoid hyperplasia presenting as a red choroidal tumor

Presenter: Puneet Jain (India)

11:51 a.m. - 11:54 a.m.

Intraocular meningioma: A growing intraocular mass

Presenter: Hakan Demirci (United States)

11:54 a.m. - 11:57 a.m.

Identifying the origin of retinal metastasis simulating cytomegalovirus retinitis in a patient with multiple primary systemic cancers

Presenter: Filiberto Altomare (Canada)

11:57 a.m. - 12:00 p.m.

Regression of retinal astrocytic hamartoma on Everolimus (42-O-rapamycin) with anatomic restoration

Presenter: Katherine Paton (Canada)

12:00 p.m. - 12:03 p.m.

Anterior chamber infiltration in a child

Presenter: Vicktoria (vicky) Vishnevskia-Dai (Israel)

12:03 p.m. - 12:06 p.m.

A mystery anterior segment tumor

Presenter: Shahar Frenkel (Israel)

12:06 p.m. - 12:09 p.m.

Advanced Coats disease: An atypical case associated with retinal dysplasia and retinoma-like features

Presenter: Theodora Hadjistilianou (Italy)

12:09 p.m. - 12:12 p.m.

Neuroendocrine metastatic uveal tumor

Presenter: Mariana Dias (Brazil)

12:12 p.m. - 12:15 p.m.

Growing choroidal osteoma: Treatment with proton beam radiation

Presenter: Janani Singaravelu (United States)

Educational Course for General Ophthalmologists

11:50 a.m. - 01:00 p.m.

Lunch Educational Course for General Ophthalmologists

12:30 p.m. - 01:15 p.m.

Johannes Vermeer and Frans van Mieris

Industry Presentation Immunocore - Does the differing Biology of Uveal Melanoma lead to different treatment options?

12:30 p.m. - 12:45 p.m.

Metastatic UM: Overview of Checkpoint inhibitors and other systemic agents- who to treat and when?

Presenter: Ellen Kapiteijn (The Netherlands)

12:46 p.m. - 01:00 p.m.

Metastatic UM: Tebentafusp - who to treat and when?

Presenter: Paul Nathan (United Kingdom)

01:01 p.m. - 01:15 p.m.

Q and A

Presenter: Richard Carvajal (United States)

12:30 p.m. - 01:40 p.m.

Pieter van Slingelandt

Women in Ocular Oncology Lunch

Presenters: Jesse Berry (United States), Renelle Lim (United States) & Carol L. Shields (United States)

12:30 p.m. - 01:40 p.m.

Lunch

Educational Course for General Ophthalmologists

12:30 p.m. - 03:00 p.m.

Willem van de Velde

Educational Course for General Ophthalmologists (parallel session)

01:40 p.m. - 02:00 p.m.

Johannes Vermeer and Frans van Mieris

S19 President's Lecture

01:40 p.m. - 01:45 p.m.

Introducing Dr Damato

Presenter: Katherine Paton (Canada)

01:45 p.m. - 02:00 p.m.

President's Lecture

Presenter: Bertil Damato (United Kingdom/Sweden)

02:00 p.m. - 03:00 p.m.

Johannes Vermeer and Frans van Mieris

S20 Conjunctiva, Lid, Orbit: Basic Science

Moderators: Carol Karp (United States), Sara Lally (United States), Alexandre Moulin (Switzerland) & Dion Paridaens (The Netherlands)

02:00 p.m. - 02:10 p.m.

The WHO Classification of Tumours, past, present and future

Presenter: Ian Cree (France)

02:10 p.m. - 02:16 p.m.

Mutational landscape and outcomes of conjunctival melanoma in 101 patients

Presenter: Sara Lally (United States)

02:16 p.m. - 02:22 p.m.

The molecular profile of conjunctival melanoma

Presenter: Lauge Hjorth Mikkelsen (Denmark)

02:22 p.m. - 02:28 p.m.

Viral and genomic drivers of carcinomas arising in the conjunctiva and the lacrimal drainage system

Presenter: Ingvild Ramberg (Denmark)

02:28 p.m. - 02:34 p.m.

High throughput drug screening in conjunctival melanoma

Presenter: Alexandre Moulin (Switzerland)

02:34 p.m. - 02:40 p.m.

Ruthenium-based photoactivated chemotherapy compounds: Activity in zebrafish tumour models

Presenter: Sylvestre Bonnet (The Netherlands)

02:40 p.m. - 02:46 p.m.

Macrophage presence relates to fewer metastases and better survival in conjunctival melanoma

Presenter: Niels Brouwer (The Netherlands)

02:46 p.m. - 02:52 p.m.

Patients presenting with conjunctival melanoma: Lessons learned from a multicenter international study

Presenter: Puneet Jain (India)

02:52 p.m. - 02:58 p.m.

Topical 1% 5-Fluorouracil as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study

Presenter: Carol Karp (United States)

04:00 p.m. - 05:00 p.m.

Academy Building - The official retirement lecture of conference president Martine Jager (invitation)

05:00 p.m. - 06:30 p.m.

Reception Academy Building (separate registration required)

06:30 p.m. - 10:00 p.m.

Buffet Botanical Gardens (invitation)

Tuesday, June 21, 2022

08:00 a.m. - 08:50 a.m.

Jan Steen

Coffee with Experts - Lymphoma

08:00 a.m. - 08:15 a.m.

The differential diagnosis of lymphoma

Presenter: Janet Davis (United States)

08:15 a.m. - 08:30 a.m.

Recognizing the pathology of lymphoma

Presenter: Robert Verdijk (The Netherlands)

08:30 a.m. - 08:40 a.m.

Types of ocular lymphoma

Presenter: Mary Beth Aronow (United States)

08:40 a.m. - 08:50 a.m.

Taking the proper biopsy of a suspicious lymphoma

Presenter: Basil Williams (United States)

08:00 a.m. - 08:50 a.m.

Willem van de Velde

Coffee with Experts - Conjunctival Tumors

08:00 a.m. - 08:50 a.m.

Educational course on ocular surface tumors

Presenters: Bita Esmaeli (United States), Hans Grossniklaus (United States), Steffen Heegaard (Denmark), Ludwig Heindl (Germany), Santosh G Honavar (India), Carol Karp (United States), Carol L. Shields (United States) & Jill Wells (United States)

08:00 a.m. - 09:00 a.m.

Godfried Schalcken

Poster session Conjunctiva, eyelid P5.1

Moderators: Priscilla Ballalai (Brazil), Randy Christopher Bowen (United States) & Rjw De Keizer (The Netherlands)

PRAME expression in conjunctival melanocytic tumours

Presenter: Debora Anconelli (Italy)

Comparative study between Rose Bengal 1% and Toluidin Blue 1% dyes in the diagnosis and evaluation of extension of OSSN- a pilot study

Presenter: Priscilla Ballalai (Brazil)

Assessing the role of adjuvant Ru106 plaque brachytherapy in conjunctival melanoma with scleral or corneal invasion

Presenter: Rolika Bansal (India)

Ocular surface squamous neoplasia: Outcomes following primary excision with 2 mm margin and cryotherapy

Presenter: Randy Christopher Bowen (United States)

Conjunctival keloid

Presenter: Ana Marisa Castello Branco (Brazil)

Ocular surface squamous neoplasia in xeroderma pigmentosa: Treatment and outcome

Presenter: Marem Chionkhumi Christy (India)

A Merkel cell carcinoma of the eyelid after previously diagnosed and treated conjunctival intraepithelial neoplasia or the development of a second tumor, even after a premalignant laesion

Presenter: Rjw De Keizer (The Netherlands)

08:00 a.m. - 09:00 a.m.

Pieter van Slingelandt

Poster session Conjunctiva, eyelid P5.2

Moderators: Mariana Dias (Brazil), Bita Esmaeli (United States) & Dion Paridaens (The Netherlands)

Squamous neoplasia after ocular trauma

Presenter: Mariana Dias (Brazil)

Adjuvant ruthenium - Plaque brachytherapy in the treatment of conjunctival melanoma

Presenter: Luise Grajewski (Germany)

The spectrum and management of tumors of the caruncle

Presenter: Leonardo Lando (Canada)

Outcomes following adjuvant strontium beta radiotherapy for conjunctival malignancies

Presenter: Stephanie Lemaitre (United Kingdom)

A rare case of conjunctival squamous cell carcinoma associated with ocular cicatricial pemphigoid

Presenter: Cinzia Mazzini (Italy)

Evaluation of adherence to topical chemotherapy treatment of Ocular Surface Squamous Neoplasia (OSSN) at a reference public health service in Brazil

Presenter: Mateus Inacio Resende (Brazil)

Sclerosant therapy for treatment of limited conjunctival vascular malformations

Presenter: Usha Singh (India)

Multimodal management of invasive squamous cell carcinoma (SCC) of orbit with globe salvage

Presenter: Sonal Yadav (India)

09:00 a.m. - 10:30 a.m.

Johannes Vermeer and Frans van Mieris

S21 Conjunctiva, Lid, Orbit, with Cases

Moderators: Ronald De Keizer (The Netherlands), Santosh G Honavar (India), Satoru Kase (Japan) & Hatem Krema (Canada)

09:00 a.m. - 09:06 a.m.

Plaque brachytherapy in the management of Ocular Surface Squamous Neoplasia with corneal, stromal and scleral invasion

Presenter: Santosh G Honavar (India)

09:06 a.m. - 09:12 a.m.

Periocular pigmented basal cell carcinomas (PBCC): Clinicopathologic features and mutational profile

Presenter: Fadi Hassanin (Saudi Arabia)

09:12 a.m. - 09:18 a.m.

Micro-RNA profiling differentiates sebaceous gland carcinoma from squamous cell carcinoma of the conjunctiva

Presenter: Ronald De Keizer (The Netherlands)

09:18 a.m. - 09:24 a.m.

Favorable response to the tyrosine kinase inhibitor apatinib in recurrent Merkel cell carcinoma

Presenter: Xin Song (China)

09:24 a.m. - 09:30 a.m.

Turf war for eyelid tumours? Plastic surgery vs ophthalmology services in a single trust

Presenter: Soyang Ella Kim (United Kingdom)

09:30 a.m. - 09:36 a.m.

Risk factors for local tumour recurrence and metastasis in sebaceous gland carcinoma of the eyelid in a large series

Presenter: Deepthi Kurian (India)

09:36 a.m. - 09:42 a.m.

Erdheim-Chester disease in a child: A case report and comprehensive review of pediatric cases

Presenter: Lauren Yeager (United States)

09:42 a.m. - 09:48 a.m.

Cyclin D1 expression and molecular genetic findings in periocular histiocytic-dendritic neoplasms

Presenter: Tatyana Milman (United States)

09:48 a.m. - 09:54 a.m.

Ocular surface specimen handling by ophthalmic surgeons - Enabling quality in pathology evaluation

Presenter: Melina Correia Morales (Brazil)

09:54 a.m. - 10:00 a.m.

Histopathological diagnosis of neoplasia from 1,912 pterygium specimens in the United Kingdom

Presenter: Hibba Quhill (United Kingdom)

10:00 a.m. - 10:06 a.m.

Adjuvant proton beam irradiation for invasive conjunctival squamous cell carcinoma: Retrospective study of 67 cases

Presenter: Alexandre Matet (France)

10:06 a.m. - 10:12 a.m.

Ocular Surface Squamous Neoplasia: Outcomes and risk factors for recurrence

Presenter: Marem Chionkhumi Christy (India)

10:12 a.m. - 10:18 a.m.

Molluscum contagiosum of the corneal limbus in an AIDS patient

Presenter: Satoru Kase (Japan)

10:18 a.m. - 10:21 a.m.

Retrograde drug embolism to retino-choroid following sclerotherapy for an orbital vascular lesion

Presenter: Usha Singh (India)

10:21 a.m. - 10:24 a.m.

Adenoid cystic carcinoma of the lacrimal gland treated with primary radical radiotherapy and concurrent chemotherapy

Presenter: Paul Cauchi (United Kingdom)

10:24 a.m. - 10:27 a.m.

Multimodality approach in extensive periocular cancers

Presenter: Hatem Krema (Canada)

10:27 a.m. - 10:30 a.m.

Orbital inflammation - Mimics and masquerades

Presenter: Fairooz P Manjandavida (India)

10:30 a.m. - 11:00 a.m.

Coffee break

10:30 a.m. - 11:00 a.m.

Godfried Schalcken

Poster session Orbit P6.1 and P6.2

Moderators: Sara Lally (United States), Fairooz P Manjandavida (India) & Matthew Wilson (United States)

Metastasis of conjunctival melanoma to the cardiac atrium

Presenter: Matthew Wilson (United States)

“Touch me not?” – A multidisciplinary enigma

Presenter: Rolika Bansal (India)

Radiation therapy for primary orbital and ocular adnexal lymphoma

Presenter: Maria Valeria Da Silva (Canada)

Intralesional triamcinolone injection in the management of orbital eosinophilic granuloma

Presenter: Deepthi Kurian (India)

Pleomorphic adenoma of the lacrimal gland: Is the name benign mixed tumor a misnomer or not?

Presenter: Sara Lally (United States)

Orbital metastases: Presenting sign of underlying malignancy - Clinical, pathological features & outcomes

Presenter: Akshay Nair (India)

Primary extraocular muscle lymphoma - A case series

Presenter: Fairooz P Manjandavida (India)

Lacrimal Gland Lymphoma – Clinical profile and outcome

Presenter: Harika Regani (India)

11:00 a.m. - 12:00 p.m.

Johannes Vermeer and Frans van Mieris

S22 Conjunctiva, Lid, Orbit, with Cases

Moderators: Bhavna Chawla (India), Tatyana Milman (United States), Kelsey Roelofs (United States) & Stijn van der Meeren (The Netherlands)

11:00 a.m. - 11:06 a.m.

Magnetic resonance imaging features of well-circumscribed orbital tumors: A multi-center study

Presenter: Kelsey Roelofs (United States)

11:06 a.m. - 11:12 a.m.

The specific location of ocular adnexal lymphoma and mortality – an international multicenter retrospective study

Presenter: Stine Vest (Denmark)

11:12 a.m. - 11:18 a.m.

Novel use of HyperArc stereotactic radiotherapy in the treatment of benign orbital apex tumours

Presenter: Alasdair Simpson (United Kingdom)

11:18 a.m. - 11:24 a.m.

Out of the ordinary

Presenter: Harika Regani (India)

11:24 a.m. - 11:30 a.m.

Bilateral uveal B-cell lymphoma with retro-orbital involvement

Presenter: Tengku Ain Kamalden (Malaysia)

11:30 a.m. - 11:36 a.m.

Fibrohistiocytoma: Simultaneous bilateral conjunctiva and skin

Presenter: Claudia Prospero Ponce (United States)

11:36 a.m. - 11:42 a.m.

Regression of recurrent conjunctival melanoma by eyedrop therapy

Presenter: Ira Seibel (Germany)

11:42 a.m. - 11:48 a.m.

Undifferentiated pleomorphic sarcoma of the conjunctiva: A case report and review of the literature

Presenter: Yuka Suimon (Japan)

11:48 a.m. - 11:54 a.m.

Sebaceous tumors of the caruncle and conjunctiva

Presenter: Mariana Dias (Brazil)

12:00 p.m. - 12:20 p.m.

Johannes Vermeer and Frans van Mieris

S23 President's Lecture

12:00 p.m. - 12:05 p.m.

Introduction of Prof Esmaeli

Presenter: Jens Folke Kiilgaard (Denmark)

12:05 p.m. - 12:20 p.m.

President's Lecture

Presenter: Bita Esmaeli (United States)

12:20 p.m. - 12:35 p.m.

Johannes Vermeer and Frans van Mieris

S24 Closing Ceremony

Presenters: Dan S. Gombos (United States), Santosh G Honavar (India), Martine Jager (The Netherlands), Fairooz P Manjandavida (India) & Vicktoria (vicky) Vishnevskia-Dai (Israel)

12:35 p.m. - 02:00 p.m.

Centre for Human Drug Research, Zernikedreef 8, Leiden

Closing Academic-Industry Lunch, Centre for Human Drug Research

Program

Program at a glance

Information

Organizing Secretariat